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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTMR8
All Species:
10
Human Site:
T581
Identified Species:
20
UniProt:
Q96EF0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96EF0
NP_060147.2
704
78919
T581
G
I
N
G
D
L
N
T
L
M
E
N
G
T
L
Chimpanzee
Pan troglodytes
XP_521093
710
79404
T581
G
I
N
G
D
L
N
T
L
M
E
N
G
T
L
Rhesus Macaque
Macaca mulatta
XP_001097351
710
79638
T581
G
I
D
G
D
L
N
T
L
M
E
N
G
T
L
Dog
Lupus familis
XP_534530
779
88802
A639
S
S
K
S
P
K
F
A
V
L
E
P
N
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE11
617
70914
W495
A
S
F
N
F
K
F
W
R
N
M
Y
H
Q
F
Rat
Rattus norvegicus
Q6AXQ4
602
69333
L480
C
R
F
G
T
F
L
L
N
C
E
A
A
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F452
629
71949
M507
Y
N
R
F
D
K
G
M
H
P
K
Q
C
V
L
Frog
Xenopus laevis
Q52KU6
602
69712
N480
R
F
G
T
F
L
Y
N
C
E
T
I
R
D
K
Zebra Danio
Brachydanio rerio
Q6TEL0
632
72485
K510
Y
D
R
G
M
H
P
K
Q
S
V
L
D
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611791
689
78732
N567
E
L
S
S
N
E
I
N
D
N
K
Y
N
Y
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22712
1006
113596
S835
K
K
E
F
N
K
L
S
V
Y
V
E
D
R
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47147
688
80133
N566
Q
Y
G
T
F
L
S
N
S
E
K
E
K
F
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
96
46
N.A.
51.5
33.3
N.A.
N.A.
59.7
34.2
52.1
N.A.
44.5
N.A.
23.5
N.A.
Protein Similarity:
100
98.8
97.6
61.8
N.A.
68
49.5
N.A.
N.A.
73
50.5
69.3
N.A.
60.3
N.A.
39
N.A.
P-Site Identity:
100
100
93.3
13.3
N.A.
0
13.3
N.A.
N.A.
13.3
6.6
20
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
0
13.3
N.A.
N.A.
20
6.6
20
N.A.
26.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
9
0
0
0
9
9
0
0
% A
% Cys:
9
0
0
0
0
0
0
0
9
9
0
0
9
0
0
% C
% Asp:
0
9
9
0
34
0
0
0
9
0
0
0
17
9
9
% D
% Glu:
9
0
9
0
0
9
0
0
0
17
42
17
0
0
9
% E
% Phe:
0
9
17
17
25
9
17
0
0
0
0
0
0
9
9
% F
% Gly:
25
0
17
42
0
0
9
0
0
0
0
0
25
0
0
% G
% His:
0
0
0
0
0
9
0
0
9
0
0
0
9
0
0
% H
% Ile:
0
25
0
0
0
0
9
0
0
0
0
9
0
0
0
% I
% Lys:
9
9
9
0
0
34
0
9
0
0
25
0
9
0
9
% K
% Leu:
0
9
0
0
0
42
17
9
25
9
0
9
0
0
42
% L
% Met:
0
0
0
0
9
0
0
9
0
25
9
0
0
0
0
% M
% Asn:
0
9
17
9
17
0
25
25
9
17
0
25
17
0
0
% N
% Pro:
0
0
0
0
9
0
9
0
0
9
0
9
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
9
0
0
9
0
9
17
% Q
% Arg:
9
9
17
0
0
0
0
0
9
0
0
0
9
17
0
% R
% Ser:
9
17
9
17
0
0
9
9
9
9
0
0
0
0
0
% S
% Thr:
0
0
0
17
9
0
0
25
0
0
9
0
0
42
0
% T
% Val:
0
0
0
0
0
0
0
0
17
0
17
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
17
9
0
0
0
0
9
0
0
9
0
17
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _