KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MOCOS
All Species:
18.18
Human Site:
S376
Identified Species:
30.77
UniProt:
Q96EN8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96EN8
NP_060417.2
888
98153
S376
A
P
V
V
R
I
Y
S
D
S
E
F
S
S
P
Chimpanzee
Pan troglodytes
XP_512097
888
98083
S376
A
P
V
V
R
I
Y
S
D
S
E
F
S
S
P
Rhesus Macaque
Macaca mulatta
XP_001105941
857
94684
S378
A
A
V
V
R
I
Y
S
D
S
E
F
S
S
P
Dog
Lupus familis
XP_547604
858
94451
V373
G
P
I
I
N
F
N
V
L
D
H
S
G
N
I
Cat
Felis silvestris
Mouse
Mus musculus
Q14CH1
862
94994
S376
A
P
V
V
R
I
Y
S
D
S
E
F
S
S
P
Rat
Rattus norvegicus
NP_001101895
698
76459
N251
D
K
M
A
S
L
Y
N
I
H
L
R
T
G
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506730
921
102647
S393
A
P
V
V
R
I
Y
S
D
T
E
F
D
D
P
Chicken
Gallus gallus
XP_419048
810
90102
G363
G
A
C
Q
M
H
L
G
I
S
D
E
D
I
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VD33
831
92380
C374
K
H
V
A
Q
I
Y
C
D
N
D
F
Q
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRA2
781
88085
I334
E
F
S
T
M
E
R
I
S
R
H
V
F
G
L
Honey Bee
Apis mellifera
XP_394734
768
86407
K321
F
L
S
I
I
S
L
K
Y
G
F
D
I
L
S
Nematode Worm
Caenorhab. elegans
Q21657
709
79704
T262
E
R
A
F
E
E
G
T
L
N
Y
Y
G
I
A
Sea Urchin
Strong. purpuratus
XP_001202774
797
88490
G350
F
D
S
V
D
H
Q
G
P
I
V
N
F
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5X8
819
91784
N372
L
Q
A
L
R
H
G
N
G
A
A
V
C
V
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
90.8
77.5
N.A.
73.9
60.1
N.A.
62.7
56.3
N.A.
49.8
N.A.
37.7
38.8
30
40.8
Protein Similarity:
100
99.3
93.1
84.1
N.A.
82.2
67.4
N.A.
74.2
69.3
N.A.
66.6
N.A.
56
58.5
48.8
57.7
P-Site Identity:
100
100
93.3
6.6
N.A.
100
6.6
N.A.
80
6.6
N.A.
40
N.A.
0
0
0
6.6
P-Site Similarity:
100
100
93.3
26.6
N.A.
100
33.3
N.A.
86.6
13.3
N.A.
60
N.A.
0
6.6
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
15
15
15
0
0
0
0
0
8
8
0
0
0
8
% A
% Cys:
0
0
8
0
0
0
0
8
0
0
0
0
8
0
8
% C
% Asp:
8
8
0
0
8
0
0
0
43
8
15
8
15
8
0
% D
% Glu:
15
0
0
0
8
15
0
0
0
0
36
8
0
0
0
% E
% Phe:
15
8
0
8
0
8
0
0
0
0
8
43
15
0
0
% F
% Gly:
15
0
0
0
0
0
15
15
8
8
0
0
15
15
0
% G
% His:
0
8
0
0
0
22
0
0
0
8
15
0
0
0
0
% H
% Ile:
0
0
8
15
8
43
0
8
15
8
0
0
8
15
15
% I
% Lys:
8
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
8
8
0
8
0
8
15
0
15
0
8
0
0
8
22
% L
% Met:
0
0
8
0
15
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
8
15
0
15
0
8
0
15
0
% N
% Pro:
0
36
0
0
0
0
0
0
8
0
0
0
0
0
36
% P
% Gln:
0
8
0
8
8
0
8
0
0
0
0
0
8
0
8
% Q
% Arg:
0
8
0
0
43
0
8
0
0
8
0
8
0
0
0
% R
% Ser:
0
0
22
0
8
8
0
36
8
36
0
8
29
36
8
% S
% Thr:
0
0
0
8
0
0
0
8
0
8
0
0
8
0
0
% T
% Val:
0
0
43
43
0
0
0
8
0
0
8
15
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
50
0
8
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _