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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MOCOS
All Species:
12.12
Human Site:
S539
Identified Species:
20.51
UniProt:
Q96EN8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96EN8
NP_060417.2
888
98153
S539
Q
E
D
A
L
T
G
S
R
V
W
N
N
S
S
Chimpanzee
Pan troglodytes
XP_512097
888
98083
S539
Q
E
D
A
L
T
G
S
R
V
W
N
N
S
S
Rhesus Macaque
Macaca mulatta
XP_001105941
857
94684
S541
Q
E
D
A
L
T
G
S
G
V
W
N
N
S
S
Dog
Lupus familis
XP_547604
858
94451
V518
D
A
P
I
A
S
G
V
C
S
D
L
P
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q14CH1
862
94994
V528
G
S
C
T
D
P
S
V
C
N
G
S
Y
P
D
Rat
Rattus norvegicus
NP_001101895
698
76459
A396
P
I
P
Q
E
K
V
A
G
I
L
N
G
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506730
921
102647
K548
E
S
N
D
V
S
R
K
D
L
P
L
D
P
E
Chicken
Gallus gallus
XP_419048
810
90102
V508
R
G
G
K
P
I
T
V
T
N
I
Y
L
Y
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VD33
831
92380
S524
S
P
D
R
M
A
V
S
E
V
T
M
S
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRA2
781
88085
Y479
L
Q
M
L
R
S
S
Y
L
A
T
K
P
L
Q
Honey Bee
Apis mellifera
XP_394734
768
86407
K466
F
G
Y
M
S
T
I
K
D
V
Q
T
L
L
V
Nematode Worm
Caenorhab. elegans
Q21657
709
79704
A407
I
N
G
T
P
T
G
A
I
R
I
S
F
G
R
Sea Urchin
Strong. purpuratus
XP_001202774
797
88490
S495
Q
R
T
T
D
E
H
S
I
T
D
A
P
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5X8
819
91784
S517
G
R
F
P
Q
L
P
S
E
D
L
E
S
K
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
90.8
77.5
N.A.
73.9
60.1
N.A.
62.7
56.3
N.A.
49.8
N.A.
37.7
38.8
30
40.8
Protein Similarity:
100
99.3
93.1
84.1
N.A.
82.2
67.4
N.A.
74.2
69.3
N.A.
66.6
N.A.
56
58.5
48.8
57.7
P-Site Identity:
100
100
93.3
13.3
N.A.
0
6.6
N.A.
0
0
N.A.
20
N.A.
0
13.3
13.3
13.3
P-Site Similarity:
100
100
93.3
26.6
N.A.
6.6
20
N.A.
40
6.6
N.A.
33.3
N.A.
13.3
13.3
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
22
8
8
0
15
0
8
0
8
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
15
0
0
0
0
0
0
% C
% Asp:
8
0
29
8
15
0
0
0
15
8
15
0
8
8
15
% D
% Glu:
8
22
0
0
8
8
0
0
15
0
0
8
0
0
15
% E
% Phe:
8
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
15
15
15
0
0
0
36
0
15
0
8
0
8
8
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
8
0
8
8
0
15
8
15
0
0
0
0
% I
% Lys:
0
0
0
8
0
8
0
15
0
0
0
8
0
15
0
% K
% Leu:
8
0
0
8
22
8
0
0
8
8
15
15
15
15
15
% L
% Met:
0
0
8
8
8
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
8
0
0
0
0
0
0
15
0
29
22
0
0
% N
% Pro:
8
8
15
8
15
8
8
0
0
0
8
0
22
15
8
% P
% Gln:
29
8
0
8
8
0
0
0
0
0
8
0
0
0
8
% Q
% Arg:
8
15
0
8
8
0
8
0
15
8
0
0
0
8
8
% R
% Ser:
8
15
0
0
8
22
15
43
0
8
0
15
15
29
22
% S
% Thr:
0
0
8
22
0
36
8
0
8
8
15
8
0
0
8
% T
% Val:
0
0
0
0
8
0
15
22
0
36
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
22
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
8
0
0
0
8
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _