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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM125A All Species: 14.85
Human Site: S50 Identified Species: 36.3
UniProt: Q96EY5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96EY5 NP_612410.1 273 28783 S50 G K S F A Q K S G Y F L C L S
Chimpanzee Pan troglodytes XP_001173577 273 28761 S50 G K S F A Q K S G Y F L C L S
Rhesus Macaque Macaca mulatta XP_001100299 123 12349
Dog Lupus familis XP_533879 311 33489 S50 G K T F A Q K S G Y F L C L S
Cat Felis silvestris
Mouse Mus musculus Q78HU3 271 28686 Y50 G F A Q K A G Y F L C L S T L
Rat Rattus norvegicus Q6P777 271 28734 Y50 G F A Q K A G Y F L C L S T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517976 332 35594 S99 G K G F A Q K S G Y F L C Y L
Chicken Gallus gallus Q5ZJX7 267 28044 A56 G Y L C V S T A A P G S A G P
Frog Xenopus laevis Q7ZYJ7 275 29879 T54 A V Y L G Y S T V P E G L E Q
Zebra Danio Brachydanio rerio Q7SXX7 275 29748 L58 F L C Y S K D L S G G M V V A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 42.1 79.4 N.A. 82 80.2 N.A. 51.2 47.2 44 43.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.2 44.3 82.9 N.A. 87.9 87.1 N.A. 64.1 68.5 66.1 61.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 93.3 N.A. 13.3 13.3 N.A. 80 6.6 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 0 100 N.A. 20 20 N.A. 80 13.3 6.6 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 20 0 40 20 0 10 10 0 0 0 10 0 10 % A
% Cys: 0 0 10 10 0 0 0 0 0 0 20 0 40 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % E
% Phe: 10 20 0 40 0 0 0 0 20 0 40 0 0 0 0 % F
% Gly: 70 0 10 0 10 0 20 0 40 10 20 10 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 40 0 0 20 10 40 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 10 10 0 0 0 10 0 20 0 60 10 30 30 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 10 % P
% Gln: 0 0 0 20 0 40 0 0 0 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 20 0 10 10 10 40 10 0 0 10 20 0 30 % S
% Thr: 0 0 10 0 0 0 10 10 0 0 0 0 0 20 0 % T
% Val: 0 10 0 0 10 0 0 0 10 0 0 0 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 10 10 0 10 0 20 0 40 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _