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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IL17RA
All Species:
7.27
Human Site:
S726
Identified Species:
22.86
UniProt:
Q96F46
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96F46
NP_055154.3
866
96122
S726
L
P
V
D
P
E
D
S
P
L
G
S
S
T
P
Chimpanzee
Pan troglodytes
XP_001173276
505
56235
K374
I
L
E
K
W
Q
K
K
K
I
A
E
M
G
P
Rhesus Macaque
Macaca mulatta
XP_001102483
865
96246
S726
L
P
V
D
P
E
D
S
P
L
G
S
T
P
M
Dog
Lupus familis
XP_543886
815
92418
P681
L
P
M
D
S
E
E
P
P
L
C
R
T
P
M
Cat
Felis silvestris
Mouse
Mus musculus
Q60943
864
97789
L727
L
P
V
D
S
D
D
L
P
L
C
S
T
P
M
Rat
Rattus norvegicus
NP_001101353
868
97931
S727
L
P
M
D
S
D
D
S
P
L
C
S
T
P
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q7T2L7
741
83535
I610
Y
L
K
T
D
V
N
I
I
S
A
G
S
S
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921444
777
88156
P638
S
E
V
V
S
Y
H
P
A
V
E
C
S
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.3
95.1
69.7
N.A.
68.2
69
N.A.
N.A.
20.8
N.A.
30.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
30.9
97
77.1
N.A.
77.9
77.7
N.A.
N.A.
37.4
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
80
40
N.A.
53.3
53.3
N.A.
N.A.
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
86.6
60
N.A.
66.6
73.3
N.A.
N.A.
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
13
0
25
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
38
13
0
0
0
% C
% Asp:
0
0
0
63
13
25
50
0
0
0
0
0
0
0
13
% D
% Glu:
0
13
13
0
0
38
13
0
0
0
13
13
0
0
13
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
25
13
0
13
0
% G
% His:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
0
0
0
0
0
13
13
13
0
0
0
13
0
% I
% Lys:
0
0
13
13
0
0
13
13
13
0
0
0
0
0
0
% K
% Leu:
63
25
0
0
0
0
0
13
0
63
0
0
0
0
0
% L
% Met:
0
0
25
0
0
0
0
0
0
0
0
0
13
0
50
% M
% Asn:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% N
% Pro:
0
63
0
0
25
0
0
25
63
0
0
0
0
50
25
% P
% Gln:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% R
% Ser:
13
0
0
0
50
0
0
38
0
13
0
50
38
13
0
% S
% Thr:
0
0
0
13
0
0
0
0
0
0
0
0
50
13
0
% T
% Val:
0
0
50
13
0
13
0
0
0
13
0
0
0
0
0
% V
% Trp:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _