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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX11
All Species:
26.06
Human Site:
S249
Identified Species:
52.12
UniProt:
Q96FC9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96FC9
NP_004390.3
970
108313
S249
F
V
H
E
V
K
K
S
P
F
G
K
D
V
R
Chimpanzee
Pan troglodytes
XP_520821
925
103112
S268
F
V
H
E
V
K
K
S
P
F
G
K
D
V
R
Rhesus Macaque
Macaca mulatta
XP_001114477
931
104280
S249
F
V
H
E
V
K
K
S
P
F
G
K
D
V
R
Dog
Lupus familis
XP_543872
907
102087
S249
F
V
H
E
V
Q
R
S
P
F
G
K
D
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6AXC6
880
98710
S221
F
V
R
E
V
L
K
S
P
F
G
K
E
T
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517598
930
104705
S266
F
V
H
E
V
Q
R
S
P
F
G
K
E
T
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569898
861
96577
N230
S
R
Q
Q
L
C
G
N
P
A
V
R
K
L
K
Honey Bee
Apis mellifera
XP_001121183
769
88327
S170
V
S
V
V
T
L
T
S
R
Q
N
Y
C
I
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792082
780
88384
R181
T
T
K
P
K
R
K
R
S
K
Q
S
L
K
A
Poplar Tree
Populus trichocarpa
XP_002299703
918
103579
T231
F
I
K
E
L
R
K
T
L
F
S
N
E
I
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22516
861
98787
Y234
N
Q
N
P
V
K
I
Y
Y
A
S
R
T
Y
S
Red Bread Mold
Neurospora crassa
A7UXD4
1073
119198
K370
P
T
P
N
P
Q
E
K
P
A
K
E
I
V
K
Conservation
Percent
Protein Identity:
100
84.4
84.2
73.4
N.A.
68.6
N.A.
N.A.
67.2
N.A.
N.A.
N.A.
N.A.
35.4
34.4
N.A.
42
Protein Similarity:
100
86.4
86.2
80.2
N.A.
76.1
N.A.
N.A.
78.4
N.A.
N.A.
N.A.
N.A.
52.1
52
N.A.
57.9
P-Site Identity:
100
100
100
80
N.A.
73.3
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
80
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
46.6
13.3
N.A.
13.3
Percent
Protein Identity:
31.1
N.A.
N.A.
N.A.
29.2
25.8
Protein Similarity:
51.2
N.A.
N.A.
N.A.
47.3
42.1
P-Site Identity:
26.6
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
66.6
N.A.
N.A.
N.A.
26.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
34
0
0
% D
% Glu:
0
0
0
59
0
0
9
0
0
0
0
9
25
0
0
% E
% Phe:
59
0
0
0
0
0
0
0
0
59
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
50
0
0
0
0
% G
% His:
0
0
42
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
9
0
0
0
0
0
9
17
0
% I
% Lys:
0
0
17
0
9
34
50
9
0
9
9
50
9
9
17
% K
% Leu:
0
0
0
0
17
17
0
0
9
0
0
0
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
9
9
0
0
0
9
0
0
9
9
0
0
17
% N
% Pro:
9
0
9
17
9
0
0
0
67
0
0
0
0
0
0
% P
% Gln:
0
9
9
9
0
25
0
0
0
9
9
0
0
0
0
% Q
% Arg:
0
9
9
0
0
17
17
9
9
0
0
17
0
0
50
% R
% Ser:
9
9
0
0
0
0
0
59
9
0
17
9
0
0
9
% S
% Thr:
9
17
0
0
9
0
9
9
0
0
0
0
9
25
0
% T
% Val:
9
50
9
9
59
0
0
0
0
0
9
0
0
34
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
9
0
0
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _