KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX11
All Species:
13.64
Human Site:
S274
Identified Species:
27.27
UniProt:
Q96FC9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96FC9
NP_004390.3
970
108313
S274
C
V
N
E
D
V
K
S
L
G
S
V
Q
L
I
Chimpanzee
Pan troglodytes
XP_520821
925
103112
S293
C
V
N
E
D
V
K
S
L
G
S
V
Q
L
I
Rhesus Macaque
Macaca mulatta
XP_001114477
931
104280
S274
C
V
N
E
D
V
K
S
L
G
S
V
Q
L
I
Dog
Lupus familis
XP_543872
907
102087
T274
C
V
N
E
D
V
K
T
L
G
S
V
Q
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6AXC6
880
98710
N246
C
V
N
E
D
V
K
N
L
G
S
V
Q
L
M
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517598
930
104705
R291
C
V
N
E
D
V
R
R
L
G
S
M
Q
L
I
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569898
861
96577
R255
D
M
A
T
K
K
A
R
P
N
P
S
K
K
S
Honey Bee
Apis mellifera
XP_001121183
769
88327
Q195
L
I
N
E
C
C
L
Q
L
Q
R
K
K
T
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792082
780
88384
V206
L
Y
K
D
R
V
A
V
E
V
M
D
M
E
Q
Poplar Tree
Populus trichocarpa
XP_002299703
918
103579
K256
C
I
N
E
E
V
L
K
L
G
S
S
V
R
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22516
861
98787
F259
L
P
S
F
P
S
S
F
R
D
K
V
P
D
E
Red Bread Mold
Neurospora crassa
A7UXD4
1073
119198
K395
C
I
N
P
T
V
N
K
L
G
T
L
A
A
I
Conservation
Percent
Protein Identity:
100
84.4
84.2
73.4
N.A.
68.6
N.A.
N.A.
67.2
N.A.
N.A.
N.A.
N.A.
35.4
34.4
N.A.
42
Protein Similarity:
100
86.4
86.2
80.2
N.A.
76.1
N.A.
N.A.
78.4
N.A.
N.A.
N.A.
N.A.
52.1
52
N.A.
57.9
P-Site Identity:
100
100
100
93.3
N.A.
86.6
N.A.
N.A.
80
N.A.
N.A.
N.A.
N.A.
0
20
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
13.3
33.3
N.A.
13.3
Percent
Protein Identity:
31.1
N.A.
N.A.
N.A.
29.2
25.8
Protein Similarity:
51.2
N.A.
N.A.
N.A.
47.3
42.1
P-Site Identity:
46.6
N.A.
N.A.
N.A.
6.6
40
P-Site Similarity:
66.6
N.A.
N.A.
N.A.
13.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
17
0
0
0
0
0
9
9
0
% A
% Cys:
67
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
9
50
0
0
0
0
9
0
9
0
9
0
% D
% Glu:
0
0
0
67
9
0
0
0
9
0
0
0
0
9
9
% E
% Phe:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
67
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
25
0
0
0
0
0
0
0
0
0
0
0
0
50
% I
% Lys:
0
0
9
0
9
9
42
17
0
0
9
9
17
9
0
% K
% Leu:
25
0
0
0
0
0
17
0
75
0
0
9
0
50
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
9
9
9
0
9
% M
% Asn:
0
0
75
0
0
0
9
9
0
9
0
0
0
0
0
% N
% Pro:
0
9
0
9
9
0
0
0
9
0
9
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
9
0
0
50
0
9
% Q
% Arg:
0
0
0
0
9
0
9
17
9
0
9
0
0
9
0
% R
% Ser:
0
0
9
0
0
9
9
25
0
0
59
17
0
0
9
% S
% Thr:
0
0
0
9
9
0
0
9
0
0
9
0
0
9
9
% T
% Val:
0
50
0
0
0
75
0
9
0
9
0
50
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _