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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX11 All Species: 10.3
Human Site: S552 Identified Species: 20.61
UniProt: Q96FC9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96FC9 NP_004390.3 970 108313 S552 L A A P A D E S Q A S T L R P
Chimpanzee Pan troglodytes XP_520821 925 103112 S571 L A A P A D E S Q A S T P R P
Rhesus Macaque Macaca mulatta XP_001114477 931 104280 S552 P A A P A D E S Q A S A P R P
Dog Lupus familis XP_543872 907 102087 D552 T P V T P V E D G E A R V P R
Cat Felis silvestris
Mouse Mus musculus Q6AXC6 880 98710 E523 P T E D S P E E G Q A V A L R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517598 930 104705 G583 G R G P T E E G E N G P P R P
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569898 861 96577 E507 K S V K R R V E D I N K E D K
Honey Bee Apis mellifera XP_001121183 769 88327 T429 Q F L N S I K T K D I E S D L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792082 780 88384 F440 P L M H I E G F L L A L T N A
Poplar Tree Populus trichocarpa XP_002299703 918 103579 F534 E G S T L S S F R A L V D M L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22516 861 98787 A504 K I D T Y N Q A L K E E E S S
Red Bread Mold Neurospora crassa A7UXD4 1073 119198 T657 H T L C S F L T A L T N L S S
Conservation
Percent
Protein Identity: 100 84.4 84.2 73.4 N.A. 68.6 N.A. N.A. 67.2 N.A. N.A. N.A. N.A. 35.4 34.4 N.A. 42
Protein Similarity: 100 86.4 86.2 80.2 N.A. 76.1 N.A. N.A. 78.4 N.A. N.A. N.A. N.A. 52.1 52 N.A. 57.9
P-Site Identity: 100 93.3 80 6.6 N.A. 6.6 N.A. N.A. 26.6 N.A. N.A. N.A. N.A. 0 0 N.A. 0
P-Site Similarity: 100 93.3 80 20 N.A. 20 N.A. N.A. 40 N.A. N.A. N.A. N.A. 13.3 26.6 N.A. 13.3
Percent
Protein Identity: 31.1 N.A. N.A. N.A. 29.2 25.8
Protein Similarity: 51.2 N.A. N.A. N.A. 47.3 42.1
P-Site Identity: 6.6 N.A. N.A. N.A. 0 6.6
P-Site Similarity: 20 N.A. N.A. N.A. 20 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 25 25 0 25 0 0 9 9 34 25 9 9 0 9 % A
% Cys: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 9 0 25 0 9 9 9 0 0 9 17 0 % D
% Glu: 9 0 9 0 0 17 50 17 9 9 9 17 17 0 0 % E
% Phe: 0 9 0 0 0 9 0 17 0 0 0 0 0 0 0 % F
% Gly: 9 9 9 0 0 0 9 9 17 0 9 0 0 0 0 % G
% His: 9 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 9 9 0 0 0 9 9 0 0 0 0 % I
% Lys: 17 0 0 9 0 0 9 0 9 9 0 9 0 0 9 % K
% Leu: 17 9 17 0 9 0 9 0 17 17 9 9 17 9 17 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 0 0 9 0 9 0 0 0 9 9 9 0 9 0 % N
% Pro: 25 9 0 34 9 9 0 0 0 0 0 9 25 9 34 % P
% Gln: 9 0 0 0 0 0 9 0 25 9 0 0 0 0 0 % Q
% Arg: 0 9 0 0 9 9 0 0 9 0 0 9 0 34 17 % R
% Ser: 0 9 9 0 25 9 9 25 0 0 25 0 9 17 17 % S
% Thr: 9 17 0 25 9 0 0 17 0 0 9 17 9 0 0 % T
% Val: 0 0 17 0 0 9 9 0 0 0 0 17 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _