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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX11 All Species: 15.15
Human Site: S593 Identified Species: 30.3
UniProt: Q96FC9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96FC9 NP_004390.3 970 108313 S593 R Q G S L S Q S T L K F L L L
Chimpanzee Pan troglodytes XP_520821 925 103112 S612 R Q G S L S Q S T L K F L L L
Rhesus Macaque Macaca mulatta XP_001114477 931 104280 S593 R Q G S L S Q S T L K F L L L
Dog Lupus familis XP_543872 907 102087 Q593 S R Q G S L S Q S S L K F L L
Cat Felis silvestris
Mouse Mus musculus Q6AXC6 880 98710 Q564 N R Q G S V G Q S S L K F L L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517598 930 104705 S624 H Q S S L S L S S L K F L L L
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569898 861 96577 T548 L A F L E T L T S N A E D G R
Honey Bee Apis mellifera XP_001121183 769 88327 H470 L N P A V H F H D I V R D A R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792082 780 88384 V481 A V H F T D V V K E A R A I I
Poplar Tree Populus trichocarpa XP_002299703 918 103579 L575 G F L K Y V M L T G E K I F S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22516 861 98787 T545 L Y C L T N L T S E G Q F F F
Red Bread Mold Neurospora crassa A7UXD4 1073 119198 S698 S P T H A F S S I A E S A R A
Conservation
Percent
Protein Identity: 100 84.4 84.2 73.4 N.A. 68.6 N.A. N.A. 67.2 N.A. N.A. N.A. N.A. 35.4 34.4 N.A. 42
Protein Similarity: 100 86.4 86.2 80.2 N.A. 76.1 N.A. N.A. 78.4 N.A. N.A. N.A. N.A. 52.1 52 N.A. 57.9
P-Site Identity: 100 100 100 13.3 N.A. 13.3 N.A. N.A. 73.3 N.A. N.A. N.A. N.A. 0 0 N.A. 0
P-Site Similarity: 100 100 100 26.6 N.A. 26.6 N.A. N.A. 80 N.A. N.A. N.A. N.A. 20 20 N.A. 13.3
Percent
Protein Identity: 31.1 N.A. N.A. N.A. 29.2 25.8
Protein Similarity: 51.2 N.A. N.A. N.A. 47.3 42.1
P-Site Identity: 6.6 N.A. N.A. N.A. 0 6.6
P-Site Similarity: 20 N.A. N.A. N.A. 20 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 9 9 0 0 0 0 9 17 0 17 9 9 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 0 0 9 0 0 0 17 0 0 % D
% Glu: 0 0 0 0 9 0 0 0 0 17 17 9 0 0 0 % E
% Phe: 0 9 9 9 0 9 9 0 0 0 0 34 25 17 9 % F
% Gly: 9 0 25 17 0 0 9 0 0 9 9 0 0 9 0 % G
% His: 9 0 9 9 0 9 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 9 0 0 9 9 9 % I
% Lys: 0 0 0 9 0 0 0 0 9 0 34 25 0 0 0 % K
% Leu: 25 0 9 17 34 9 25 9 0 34 17 0 34 50 50 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 9 9 0 0 0 9 0 0 0 9 0 0 0 0 0 % N
% Pro: 0 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 34 17 0 0 0 25 17 0 0 0 9 0 0 0 % Q
% Arg: 25 17 0 0 0 0 0 0 0 0 0 17 0 9 17 % R
% Ser: 17 0 9 34 17 34 17 42 42 17 0 9 0 0 9 % S
% Thr: 0 0 9 0 17 9 0 17 34 0 0 0 0 0 0 % T
% Val: 0 9 0 0 9 17 9 9 0 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _