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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIK3IP1 All Species: 16.67
Human Site: T252 Identified Species: 40.74
UniProt: Q96FE7 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96FE7 NP_443112.2 263 28248 T252 V D P Q E G T T P L M G Q A G
Chimpanzee Pan troglodytes XP_530409 263 28215 T252 V D P Q E G S T P L M G Q A G
Rhesus Macaque Macaca mulatta XP_001110756 263 28282 T252 V D P Q E G S T P L M G Q A G
Dog Lupus familis XP_543490 268 28926 A257 V D L Q E G S A P L M G Q A G
Cat Felis silvestris
Mouse Mus musculus Q7TMJ8 264 28549 T253 A D V Q E G S T L L T G Q A G
Rat Rattus norvegicus Q56A20 246 26895 T235 A D V Q E G S T L L T D Q A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506082 218 23528 P208 D V R E G N A P L M G Q A G T
Chicken Gallus gallus XP_415257 271 29163 S259 V E D T H D G S G P L M G Q A
Frog Xenopus laevis Q90Y90 452 50170 A402 L H I S M K S A R L A S S S S
Zebra Danio Brachydanio rerio Q7SXB3 263 28758 V248 Q T P T Q E P V E G A D P L M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 96.1 84.3 N.A. 78.7 77.5 N.A. 50.5 56.8 21 47.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.2 98 90.3 N.A. 85.6 82.8 N.A. 62.3 69.7 33.6 62.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 93.3 80 N.A. 66.6 60 N.A. 0 6.6 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 73.3 66.6 N.A. 13.3 26.6 26.6 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 0 0 0 0 10 20 0 0 20 0 10 60 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 60 10 0 0 10 0 0 0 0 0 20 0 0 0 % D
% Glu: 0 10 0 10 60 10 0 0 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 60 10 0 10 10 10 50 10 10 60 % G
% His: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 10 0 0 0 0 0 30 70 10 0 0 10 0 % L
% Met: 0 0 0 0 10 0 0 0 0 10 40 10 0 0 10 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 40 0 0 0 10 10 40 10 0 0 10 0 0 % P
% Gln: 10 0 0 60 10 0 0 0 0 0 0 10 60 10 0 % Q
% Arg: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 0 0 0 10 0 0 60 10 0 0 0 10 10 10 10 % S
% Thr: 0 10 0 20 0 0 10 50 0 0 20 0 0 0 10 % T
% Val: 50 10 20 0 0 0 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _