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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIK3IP1
All Species:
27.58
Human Site:
Y192
Identified Species:
67.41
UniProt:
Q96FE7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96FE7
NP_443112.2
263
28248
Y192
G
A
G
I
I
L
G
Y
S
Y
K
R
G
K
D
Chimpanzee
Pan troglodytes
XP_530409
263
28215
Y192
G
A
G
I
I
L
G
Y
S
Y
K
R
G
K
D
Rhesus Macaque
Macaca mulatta
XP_001110756
263
28282
Y192
G
A
G
I
I
L
G
Y
S
Y
K
R
G
K
D
Dog
Lupus familis
XP_543490
268
28926
Y197
G
A
G
I
V
L
G
Y
T
Y
K
R
G
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMJ8
264
28549
Y193
G
A
G
I
I
V
G
Y
T
Y
K
R
G
K
D
Rat
Rattus norvegicus
Q56A20
246
26895
D182
Y
T
Y
K
R
G
K
D
L
K
E
Q
H
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506082
218
23528
E156
K
R
G
K
D
L
K
E
Q
H
E
Q
R
M
F
Chicken
Gallus gallus
XP_415257
271
29163
Y199
G
A
G
I
V
V
G
Y
I
Y
K
R
G
K
D
Frog
Xenopus laevis
Q90Y90
452
50170
Y316
A
Q
G
F
S
V
V
Y
E
A
F
K
E
E
T
Zebra Danio
Brachydanio rerio
Q7SXB3
263
28758
Y188
G
G
G
I
T
M
G
Y
F
Y
K
R
G
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
96.1
84.3
N.A.
78.7
77.5
N.A.
50.5
56.8
21
47.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
98
90.3
N.A.
85.6
82.8
N.A.
62.3
69.7
33.6
62.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
0
N.A.
13.3
80
13.3
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
33.3
93.3
33.3
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
60
0
0
0
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
70
% D
% Glu:
0
0
0
0
0
0
0
10
10
0
20
0
10
20
0
% E
% Phe:
0
0
0
10
0
0
0
0
10
0
10
0
0
0
10
% F
% Gly:
70
10
90
0
0
10
70
0
0
0
0
0
70
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% H
% Ile:
0
0
0
70
40
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
10
0
0
20
0
0
20
0
0
10
70
10
0
60
0
% K
% Leu:
0
0
0
0
0
50
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
10
0
0
20
0
0
10
% Q
% Arg:
0
10
0
0
10
0
0
0
0
0
0
70
10
10
0
% R
% Ser:
0
0
0
0
10
0
0
0
30
0
0
0
0
0
0
% S
% Thr:
0
10
0
0
10
0
0
0
20
0
0
0
0
0
10
% T
% Val:
0
0
0
0
20
30
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
10
0
0
0
0
80
0
70
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _