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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEIL1
All Species:
8.79
Human Site:
S381
Identified Species:
24.17
UniProt:
Q96FI4
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96FI4
NP_078884.2
390
43684
S381
K
V
K
A
D
I
P
S
L
E
P
E
G
T
S
Chimpanzee
Pan troglodytes
XP_001143488
390
43734
S381
K
V
K
A
D
I
P
S
L
E
P
E
G
T
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_854395
389
42884
S381
R
I
K
A
N
T
R
S
L
E
E
G
M
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4Q6
389
43567
R381
T
I
P
D
T
R
P
R
E
A
G
E
S
S
A
Rat
Rattus norvegicus
NP_001020925
387
43330
R379
S
K
P
D
T
Q
P
R
E
A
G
E
I
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518546
515
56129
E469
E
I
T
A
G
G
G
E
T
H
R
E
G
G
C
Chicken
Gallus gallus
NP_001074345
363
40448
R355
R
N
R
T
S
A
R
R
G
R
G
A
A
P
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956577
437
49897
T421
V
N
K
K
N
F
T
T
C
R
K
S
K
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141023
384
42146
A365
F
G
Q
A
N
S
D
A
V
D
K
S
D
R
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
N.A.
78.9
N.A.
80
78.9
N.A.
51.8
50.7
N.A.
45.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.7
N.A.
85.3
N.A.
87.1
85.9
N.A.
60.9
64.3
N.A.
61.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
33.3
N.A.
13.3
13.3
N.A.
20
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
66.6
N.A.
33.3
26.6
N.A.
33.3
20
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
21
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
37.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
56
0
12
0
12
0
23
0
12
12
0
56
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
12
% C
% Asp:
0
0
0
23
23
0
12
0
0
12
0
0
12
0
0
% D
% Glu:
12
0
0
0
0
0
0
12
23
34
12
56
0
0
0
% E
% Phe:
12
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
0
0
12
12
12
0
12
0
34
12
34
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
0
34
0
0
0
23
0
0
0
0
0
0
12
0
0
% I
% Lys:
23
12
45
12
0
0
0
0
0
0
23
0
12
0
12
% K
% Leu:
0
0
0
0
0
0
0
0
34
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
0
23
0
0
34
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
23
0
0
0
45
0
0
0
23
0
0
12
0
% P
% Gln:
0
0
12
0
0
12
0
0
0
0
0
0
0
0
0
% Q
% Arg:
23
0
12
0
0
12
23
34
0
23
12
0
0
12
0
% R
% Ser:
12
0
0
0
12
12
0
34
0
0
0
23
12
34
23
% S
% Thr:
12
0
12
12
23
12
12
12
12
0
0
0
0
34
0
% T
% Val:
12
23
0
0
0
0
0
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _