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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR89
All Species:
26.06
Human Site:
S166
Identified Species:
47.78
UniProt:
Q96FK6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96FK6
NP_001008726.1
387
43215
S166
K
D
S
L
G
A
Y
S
E
T
H
S
D
D
V
Chimpanzee
Pan troglodytes
XP_509999
387
43209
S166
K
D
P
L
G
A
Y
S
E
T
H
S
D
D
V
Rhesus Macaque
Macaca mulatta
XP_001100607
387
43031
S166
K
D
P
L
G
A
Y
S
E
T
H
S
D
D
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0R9
386
42451
S165
R
D
P
L
G
A
Y
S
E
T
H
S
D
D
I
Rat
Rattus norvegicus
Q5FVP5
386
42731
S165
R
D
P
L
G
A
Y
S
E
T
H
S
D
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506882
386
42174
S164
T
P
P
L
G
V
Y
S
E
S
H
N
D
D
I
Chicken
Gallus gallus
XP_421411
389
42531
S170
R
E
P
L
G
V
Y
S
E
S
H
N
D
D
V
Frog
Xenopus laevis
NP_001085686
383
42623
A167
Q
D
P
L
G
V
Y
A
E
S
H
F
D
D
I
Zebra Danio
Brachydanio rerio
XP_001343307
379
41317
D160
V
Y
S
E
S
H
S
D
D
V
T
A
V
K
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724865
341
37834
E134
G
V
Y
F
E
S
H
E
D
D
I
T
S
L
R
Honey Bee
Apis mellifera
XP_623934
401
44611
W189
N
N
L
L
G
G
Y
W
E
S
H
M
E
D
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788954
397
43807
K160
T
N
L
L
G
T
Y
K
E
S
H
S
D
D
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53962
389
43830
S168
V
N
I
L
L
S
G
S
T
D
G
Y
T
N
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.6
N.A.
N.A.
80.8
81.6
N.A.
65.1
63.2
55.5
42.8
N.A.
28.1
26.1
N.A.
39.2
Protein Similarity:
100
99.4
97.9
N.A.
N.A.
89.6
90.6
N.A.
80.6
78.6
75.4
65.1
N.A.
43.9
45.1
N.A.
56.6
P-Site Identity:
100
93.3
93.3
N.A.
N.A.
80
80
N.A.
53.3
60
53.3
6.6
N.A.
0
46.6
N.A.
53.3
P-Site Similarity:
100
93.3
93.3
N.A.
N.A.
93.3
93.3
N.A.
73.3
86.6
80
20
N.A.
26.6
66.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
39
0
8
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
47
0
0
0
0
0
8
16
16
0
0
70
77
0
% D
% Glu:
0
8
0
8
8
0
0
8
77
0
0
0
8
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
8
% F
% Gly:
8
0
0
0
77
8
8
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
8
8
0
0
0
77
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
47
% I
% Lys:
24
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% K
% Leu:
0
0
16
85
8
0
0
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
24
0
0
0
0
0
0
0
0
0
16
0
8
0
% N
% Pro:
0
8
54
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
24
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
16
0
8
16
8
62
0
39
0
47
8
0
0
% S
% Thr:
16
0
0
0
0
8
0
0
8
39
8
8
8
0
0
% T
% Val:
16
8
0
0
0
24
0
0
0
8
0
0
8
0
39
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
0
77
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _