KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR89
All Species:
37.58
Human Site:
S188
Identified Species:
68.89
UniProt:
Q96FK6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96FK6
NP_001008726.1
387
43215
S188
S
N
P
N
M
V
V
S
G
S
S
D
G
L
V
Chimpanzee
Pan troglodytes
XP_509999
387
43209
S188
S
N
P
N
M
V
V
S
G
S
S
D
G
L
V
Rhesus Macaque
Macaca mulatta
XP_001100607
387
43031
S188
S
D
P
N
M
V
V
S
G
S
S
D
G
L
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0R9
386
42451
S187
S
N
P
N
L
V
V
S
G
S
T
D
G
L
V
Rat
Rattus norvegicus
Q5FVP5
386
42731
S187
S
N
P
N
M
V
V
S
G
S
T
D
G
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506882
386
42174
S186
N
D
P
N
T
I
V
S
G
S
T
D
G
L
V
Chicken
Gallus gallus
XP_421411
389
42531
S192
V
K
P
S
L
V
V
S
G
S
T
D
G
L
V
Frog
Xenopus laevis
NP_001085686
383
42623
S189
T
N
P
S
M
V
A
S
G
S
T
D
G
L
V
Zebra Danio
Brachydanio rerio
XP_001343307
379
41317
G182
L
A
S
G
G
T
D
G
L
V
N
V
F
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724865
341
37834
D156
L
L
A
T
G
S
V
D
G
L
V
N
V
F
D
Honey Bee
Apis mellifera
XP_623934
401
44611
S211
S
K
Q
D
V
L
A
S
G
S
T
D
G
L
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788954
397
43807
T182
T
K
S
S
S
L
A
T
G
S
T
D
G
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53962
389
43830
V190
E
E
D
A
L
H
Q
V
I
N
Y
A
S
I
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.6
N.A.
N.A.
80.8
81.6
N.A.
65.1
63.2
55.5
42.8
N.A.
28.1
26.1
N.A.
39.2
Protein Similarity:
100
99.4
97.9
N.A.
N.A.
89.6
90.6
N.A.
80.6
78.6
75.4
65.1
N.A.
43.9
45.1
N.A.
56.6
P-Site Identity:
100
100
93.3
N.A.
N.A.
86.6
93.3
N.A.
66.6
66.6
73.3
0
N.A.
13.3
46.6
N.A.
40
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
93.3
86.6
93.3
13.3
N.A.
20
80
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
0
24
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
8
8
0
0
8
8
0
0
0
77
0
8
8
% D
% Glu:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% F
% Gly:
0
0
0
8
16
0
0
8
85
0
0
0
77
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
8
0
0
8
0
0
0
0
8
8
% I
% Lys:
0
24
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
16
8
0
0
24
16
0
0
8
8
0
0
0
77
8
% L
% Met:
0
0
0
0
39
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
39
0
47
0
0
0
0
0
8
8
8
0
0
0
% N
% Pro:
0
0
62
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
47
0
16
24
8
8
0
70
0
77
24
0
8
0
0
% S
% Thr:
16
0
0
8
8
8
0
8
0
0
54
0
0
0
0
% T
% Val:
8
0
0
0
8
54
62
8
0
8
8
8
8
0
70
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _