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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR89
All Species:
34.24
Human Site:
S335
Identified Species:
62.78
UniProt:
Q96FK6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96FK6
NP_001008726.1
387
43215
S335
C
W
N
V
Q
D
D
S
L
L
T
G
G
E
D
Chimpanzee
Pan troglodytes
XP_509999
387
43209
S335
C
W
N
V
Q
D
D
S
L
L
T
G
G
E
D
Rhesus Macaque
Macaca mulatta
XP_001100607
387
43031
S335
C
W
N
V
Q
D
D
S
L
L
T
G
G
E
D
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0R9
386
42451
S334
C
W
N
V
S
E
D
S
L
L
T
G
G
E
D
Rat
Rattus norvegicus
Q5FVP5
386
42731
S334
C
W
T
V
S
E
D
S
L
L
T
G
G
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506882
386
42174
G333
S
F
C
W
N
P
E
G
D
S
L
L
T
G
G
Chicken
Gallus gallus
XP_421411
389
42531
S339
C
W
N
P
A
E
E
S
L
L
T
G
G
E
D
Frog
Xenopus laevis
NP_001085686
383
42623
S334
Y
W
N
F
E
D
D
S
L
L
T
G
G
E
D
Zebra Danio
Brachydanio rerio
XP_001343307
379
41317
S325
Q
W
D
A
I
G
R
S
L
V
T
G
G
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724865
341
37834
L293
K
Q
I
V
R
D
S
L
F
D
S
K
R
S
L
Honey Bee
Apis mellifera
XP_623934
401
44611
S353
W
L
H
E
K
S
G
S
L
I
T
V
G
E
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788954
397
43807
T324
H
W
D
N
Q
T
E
T
L
V
T
G
G
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53962
389
43830
K339
N
F
W
D
Y
S
K
K
M
N
V
L
G
D
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.6
N.A.
N.A.
80.8
81.6
N.A.
65.1
63.2
55.5
42.8
N.A.
28.1
26.1
N.A.
39.2
Protein Similarity:
100
99.4
97.9
N.A.
N.A.
89.6
90.6
N.A.
80.6
78.6
75.4
65.1
N.A.
43.9
45.1
N.A.
56.6
P-Site Identity:
100
100
100
N.A.
N.A.
86.6
80
N.A.
0
73.3
80
53.3
N.A.
13.3
33.3
N.A.
53.3
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
86.6
N.A.
13.3
86.6
86.6
66.6
N.A.
26.6
53.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
47
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
16
8
0
39
47
0
8
8
0
0
0
8
77
% D
% Glu:
0
0
0
8
8
24
24
0
0
0
0
0
0
77
0
% E
% Phe:
0
16
0
8
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
8
8
0
0
0
70
85
8
16
% G
% His:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
8
0
0
0
8
0
8
8
0
0
0
8
0
0
0
% K
% Leu:
0
8
0
0
0
0
0
8
77
54
8
16
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
8
0
47
8
8
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
8
0
0
31
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
8
0
0
0
0
0
8
0
0
% R
% Ser:
8
0
0
0
16
16
8
70
0
8
8
0
0
8
0
% S
% Thr:
0
0
8
0
0
8
0
8
0
0
77
0
8
0
0
% T
% Val:
0
0
0
47
0
0
0
0
0
16
8
8
0
0
0
% V
% Trp:
8
70
8
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _