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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR89
All Species:
34.24
Human Site:
Y276
Identified Species:
62.78
UniProt:
Q96FK6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96FK6
NP_001008726.1
387
43215
Y276
M
K
E
D
A
L
D
Y
L
I
G
G
L
Y
H
Chimpanzee
Pan troglodytes
XP_509999
387
43209
Y276
M
K
E
D
A
L
D
Y
L
I
G
G
L
Y
H
Rhesus Macaque
Macaca mulatta
XP_001100607
387
43031
Y276
M
K
E
D
S
L
D
Y
L
I
G
G
L
Y
H
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0R9
386
42451
Y275
V
K
D
G
H
L
D
Y
L
I
G
G
L
Y
H
Rat
Rattus norvegicus
Q5FVP5
386
42731
Y275
V
K
E
G
H
L
D
Y
L
I
G
G
L
Y
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506882
386
42174
Y274
V
K
N
D
H
L
H
Y
L
I
G
G
V
Y
H
Chicken
Gallus gallus
XP_421411
389
42531
Y280
I
E
N
G
S
L
N
Y
L
V
G
G
M
Y
H
Frog
Xenopus laevis
NP_001085686
383
42623
Y275
F
A
T
H
N
I
D
Y
M
I
G
G
I
Y
H
Zebra Danio
Brachydanio rerio
XP_001343307
379
41317
Y266
P
D
G
V
S
L
E
Y
F
I
G
G
T
W
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724865
341
37834
K234
T
A
A
I
R
R
K
K
A
A
N
F
N
L
I
Honey Bee
Apis mellifera
XP_623934
401
44611
V294
D
P
D
D
C
Y
I
V
R
F
H
A
S
N
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788954
397
43807
Y265
E
D
R
C
K
V
D
Y
L
V
D
C
F
Y
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53962
389
43830
T280
F
K
D
E
K
V
D
T
E
N
G
I
V
I
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.6
N.A.
N.A.
80.8
81.6
N.A.
65.1
63.2
55.5
42.8
N.A.
28.1
26.1
N.A.
39.2
Protein Similarity:
100
99.4
97.9
N.A.
N.A.
89.6
90.6
N.A.
80.6
78.6
75.4
65.1
N.A.
43.9
45.1
N.A.
56.6
P-Site Identity:
100
100
93.3
N.A.
N.A.
73.3
80
N.A.
66.6
46.6
46.6
33.3
N.A.
0
6.6
N.A.
33.3
P-Site Similarity:
100
100
100
N.A.
N.A.
86.6
86.6
N.A.
80
86.6
66.6
53.3
N.A.
0
13.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
0
16
0
0
0
8
8
0
8
0
0
8
% A
% Cys:
0
0
0
8
8
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
16
24
39
0
0
62
0
0
0
8
0
0
0
0
% D
% Glu:
8
8
31
8
0
0
8
0
8
0
0
0
0
0
0
% E
% Phe:
16
0
0
0
0
0
0
0
8
8
0
8
8
0
0
% F
% Gly:
0
0
8
24
0
0
0
0
0
0
77
70
0
0
0
% G
% His:
0
0
0
8
24
0
8
0
0
0
8
0
0
0
70
% H
% Ile:
8
0
0
8
0
8
8
0
0
62
0
8
8
8
8
% I
% Lys:
0
54
0
0
16
0
8
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
62
0
0
62
0
0
0
39
8
8
% L
% Met:
24
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% M
% Asn:
0
0
16
0
8
0
8
0
0
8
8
0
8
8
0
% N
% Pro:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
8
8
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
24
0
0
0
0
0
0
0
8
0
0
% S
% Thr:
8
0
8
0
0
0
0
8
0
0
0
0
8
0
0
% T
% Val:
24
0
0
8
0
16
0
8
0
16
0
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
8
0
77
0
0
0
0
0
70
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _