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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC47A1 All Species: 25.15
Human Site: S538 Identified Species: 61.48
UniProt: Q96FL8 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96FL8 NP_060712.2 570 61922 S538 P Q D G A K L S R K Q L V L R
Chimpanzee Pan troglodytes XP_001144887 570 61885 S538 P Q D G A K L S R K Q L V L R
Rhesus Macaque Macaca mulatta XP_001101770 580 62503 S548 S A S A S R L S V K Q L V I R
Dog Lupus familis XP_546648 832 88678 T653 P T G T A T L T G S Q L L L R
Cat Felis silvestris
Mouse Mus musculus Q8K0H1 567 61623 S535 P K D S N K L S G K Q L A L R
Rat Rattus norvegicus Q5I0E9 566 61421 S534 P K D S N K L S G K Q L A L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508139 746 80212 S716 A E D V K T L S L K E L V L R
Chicken Gallus gallus NP_001129151 579 62641 S548 A L P G A A P S R G L I L R R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A1L1P9 590 63741 T556 T T V G A V L T T K Q L I V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LYT3 507 55129 A488 W T S E V E N A A Q R V K T S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 48.6 50.2 N.A. 78.2 78.5 N.A. 52.6 49.4 N.A. 50 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 63.9 59.6 N.A. 86.3 86.4 N.A. 62.7 67.8 N.A. 68.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 46.6 46.6 N.A. 66.6 66.6 N.A. 53.3 33.3 N.A. 46.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 66.6 60 N.A. 73.3 73.3 N.A. 66.6 46.6 N.A. 66.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 46.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 10 0 10 50 10 0 10 10 0 0 0 20 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 10 0 10 0 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 40 0 0 0 0 30 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 10 10 10 0 % I
% Lys: 0 20 0 0 10 40 0 0 0 70 0 0 10 0 0 % K
% Leu: 0 10 0 0 0 0 80 0 10 0 10 80 20 60 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 20 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 50 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % P
% Gln: 0 20 0 0 0 0 0 0 0 10 70 0 0 0 0 % Q
% Arg: 0 0 0 0 0 10 0 0 30 0 10 0 0 10 90 % R
% Ser: 10 0 20 20 10 0 0 70 0 10 0 0 0 0 10 % S
% Thr: 10 30 0 10 0 20 0 20 10 0 0 0 0 10 0 % T
% Val: 0 0 10 10 10 10 0 0 10 0 0 10 40 10 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _