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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPNE2
All Species:
19.39
Human Site:
S250
Identified Species:
42.67
UniProt:
Q96FN4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96FN4
NP_689940.3
548
61190
S250
G
E
F
Q
T
S
V
S
Q
M
C
E
A
R
D
Chimpanzee
Pan troglodytes
XP_510986
548
61113
S250
G
E
F
Q
T
S
V
S
Q
M
C
E
A
R
D
Rhesus Macaque
Macaca mulatta
XP_001095881
548
61185
S250
G
E
F
Q
T
S
V
S
Q
M
C
E
A
R
D
Dog
Lupus familis
XP_535289
548
60977
S250
G
E
F
Q
T
S
V
S
Q
M
C
E
A
R
D
Cat
Felis silvestris
Mouse
Mus musculus
P59108
548
61017
L250
G
E
F
Q
T
S
V
L
Q
M
S
E
A
R
D
Rat
Rattus norvegicus
Q5BJS7
553
61792
S246
T
T
S
Y
R
E
L
S
K
A
Q
N
Q
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511484
446
49634
S174
S
G
I
I
I
V
R
S
C
K
I
T
R
E
Y
Chicken
Gallus gallus
XP_001232390
544
60655
A246
G
E
F
Q
T
S
V
A
R
M
C
E
A
Q
D
Frog
Xenopus laevis
NP_001088611
533
59322
Y247
S
R
S
S
P
M
E
Y
E
C
I
N
E
K
K
Zebra Danio
Brachydanio rerio
NP_001038540
563
62810
T266
G
E
F
Q
T
S
V
T
K
M
S
E
A
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XUB9
634
71083
R269
R
G
D
A
K
F
S
R
D
D
L
I
G
T
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.4
97
N.A.
94.5
49.3
N.A.
68
88.8
62.4
77.6
N.A.
N.A.
N.A.
35.7
N.A.
Protein Similarity:
100
99.8
99.8
98.7
N.A.
97.8
69.4
N.A.
73.7
94.7
78
87.3
N.A.
N.A.
N.A.
50.3
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
6.6
N.A.
6.6
80
0
66.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
20
N.A.
6.6
100
13.3
86.6
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
10
0
10
0
0
64
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
10
46
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
10
10
0
0
0
0
55
% D
% Glu:
0
64
0
0
0
10
10
0
10
0
0
64
10
19
0
% E
% Phe:
0
0
64
0
0
10
0
0
0
0
0
0
0
10
0
% F
% Gly:
64
19
0
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
10
10
0
0
0
0
0
19
10
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
19
10
0
0
0
10
10
% K
% Leu:
0
0
0
0
0
0
10
10
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
64
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
10
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
64
0
0
0
0
46
0
10
0
10
10
0
% Q
% Arg:
10
10
0
0
10
0
10
10
10
0
0
0
10
46
0
% R
% Ser:
19
0
19
10
0
64
10
55
0
0
19
0
0
0
0
% S
% Thr:
10
10
0
0
64
0
0
10
0
0
0
10
0
10
10
% T
% Val:
0
0
0
0
0
10
64
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _