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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF12 All Species: 10
Human Site: S534 Identified Species: 24.44
UniProt: Q96FN5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96FN5 NP_612433.1 646 70660 S534 Q V L D P E A S G G R P P S A
Chimpanzee Pan troglodytes XP_520205 620 67735 S508 Q V L D P E A S G G R P P S A
Rhesus Macaque Macaca mulatta XP_001100472 652 71507 S540 Q V L D P E A S G G R P P S A
Dog Lupus familis XP_538808 662 71853 P550 Q V M S P K A P G D M P L C A
Cat Felis silvestris
Mouse Mus musculus NP_034746 642 70687 P530 Q V L E P E A P G H I S Q S V
Rat Rattus norvegicus NP_001012102 647 71018 P535 Q V L E P E A P G H I S P S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425403 585 63430 F482 L Y G L L R D F V V E N E Q L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524883 844 92965 A703 E Q R M S E N A N R R T D T A
Honey Bee Apis mellifera XP_394435 796 89098 Y638 K R R I V G S Y N N I V E A Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798047 1153 125226 H861 H P T M G Q S H P S T H R G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.5 94.9 84.8 N.A. 81.1 79.9 N.A. N.A. 44.5 N.A. N.A. N.A. 25.8 29.5 N.A. 25
Protein Similarity: 100 95.9 96 88.6 N.A. 85.7 85.3 N.A. N.A. 56.3 N.A. N.A. N.A. 40.8 45.9 N.A. 35.9
P-Site Identity: 100 100 100 46.6 N.A. 53.3 60 N.A. N.A. 0 N.A. N.A. N.A. 20 0 N.A. 0
P-Site Similarity: 100 100 100 60 N.A. 60 66.6 N.A. N.A. 0 N.A. N.A. N.A. 40 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 60 10 0 0 0 0 0 10 50 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 30 0 0 10 0 0 10 0 0 10 0 0 % D
% Glu: 10 0 0 20 0 60 0 0 0 0 10 0 20 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 10 10 0 0 60 30 0 0 0 10 0 % G
% His: 10 0 0 0 0 0 0 10 0 20 0 10 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 30 0 0 0 0 % I
% Lys: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 50 10 10 0 0 0 0 0 0 0 10 0 10 % L
% Met: 0 0 10 20 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 20 10 0 10 0 0 0 % N
% Pro: 0 10 0 0 60 0 0 30 10 0 0 40 40 0 0 % P
% Gln: 60 10 0 0 0 10 0 0 0 0 0 0 10 10 0 % Q
% Arg: 0 10 20 0 0 10 0 0 0 10 40 0 10 0 0 % R
% Ser: 0 0 0 10 10 0 20 30 0 10 0 20 0 50 10 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 10 10 0 10 0 % T
% Val: 0 60 0 0 10 0 0 0 10 10 0 10 0 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _