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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SIPA1 All Species: 4.55
Human Site: S148 Identified Species: 14.29
UniProt: Q96FS4 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96FS4 NP_006738.3 1042 112149 S148 A S S G T L A S A E D Q A A S
Chimpanzee Pan troglodytes XP_510040 1804 199959 A363 R R N T T T G A S A A A V A S
Rhesus Macaque Macaca mulatta XP_001113287 1048 112448 S148 A S S G T L A S A D D Q A A S
Dog Lupus familis XP_540851 845 91357 V43 E A L G P V A V S L R R E E K
Cat Felis silvestris
Mouse Mus musculus P46062 1037 112047 E146 A N S G T L A E G Q T T T S D
Rat Rattus norvegicus O35412 1822 201906 A363 R R N T T T G A S A A A V A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJY3 917 103751 F115 T D S E K N P F F L S V V L S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_682857 1230 136495 A247 K K N I T S G A S A A S Q L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.4 97.4 73.1 N.A. 88.7 28.2 N.A. N.A. 22.7 N.A. 41.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 39.6 98 76.1 N.A. 92.5 39.6 N.A. N.A. 38.3 N.A. 56.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 20 93.3 13.3 N.A. 40 20 N.A. N.A. 13.3 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 40 100 40 N.A. 60 40 N.A. N.A. 13.3 N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 38 13 0 0 0 0 50 38 25 38 38 25 25 50 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 13 0 0 0 0 0 0 0 13 25 0 0 0 13 % D
% Glu: 13 0 0 13 0 0 0 13 0 13 0 0 13 13 0 % E
% Phe: 0 0 0 0 0 0 0 13 13 0 0 0 0 0 0 % F
% Gly: 0 0 0 50 0 0 38 0 13 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 13 13 0 0 13 0 0 0 0 0 0 0 0 0 13 % K
% Leu: 0 0 13 0 0 38 0 0 0 25 0 0 0 25 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 13 38 0 0 13 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 13 0 13 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 13 0 25 13 0 0 % Q
% Arg: 25 25 0 0 0 0 0 0 0 0 13 13 0 0 13 % R
% Ser: 0 25 50 0 0 13 0 25 50 0 13 13 0 13 63 % S
% Thr: 13 0 0 25 75 25 0 0 0 0 13 13 13 0 0 % T
% Val: 0 0 0 0 0 13 0 13 0 0 0 13 38 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _