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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIPA1
All Species:
6.97
Human Site:
S253
Identified Species:
21.9
UniProt:
Q96FS4
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96FS4
NP_006738.3
1042
112149
S253
R
R
E
E
K
E
G
S
G
G
G
T
L
H
S
Chimpanzee
Pan troglodytes
XP_510040
1804
199959
S531
D
E
M
K
E
N
G
S
P
Y
N
Y
R
I
I
Rhesus Macaque
Macaca mulatta
XP_001113287
1048
112448
S253
R
R
E
E
K
E
G
S
G
G
G
T
L
H
S
Dog
Lupus familis
XP_540851
845
91357
I137
S
F
Q
R
K
V
G
I
L
Y
C
R
A
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
P46062
1037
112047
G248
L
R
R
E
E
K
E
G
S
G
G
G
T
L
H
Rat
Rattus norvegicus
O35412
1822
201906
L570
S
T
A
R
G
L
P
L
K
E
V
L
E
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJY3
917
103751
L209
L
Y
A
K
D
G
Q
L
T
D
D
E
M
F
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_682857
1230
136495
S404
E
K
E
G
S
S
G
S
Q
Y
N
Y
R
I
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.4
97.4
73.1
N.A.
88.7
28.2
N.A.
N.A.
22.7
N.A.
41.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
39.6
98
76.1
N.A.
92.5
39.6
N.A.
N.A.
38.3
N.A.
56.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
13.3
N.A.
26.6
6.6
N.A.
N.A.
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
20
N.A.
40
6.6
N.A.
N.A.
20
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
0
0
0
0
0
0
0
0
0
13
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% C
% Asp:
13
0
0
0
13
0
0
0
0
13
13
0
0
0
0
% D
% Glu:
13
13
38
38
25
25
13
0
0
13
0
13
13
0
0
% E
% Phe:
0
13
0
0
0
0
0
0
0
0
0
0
0
13
0
% F
% Gly:
0
0
0
13
13
13
63
13
25
38
38
13
0
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
38
13
% H
% Ile:
0
0
0
0
0
0
0
13
0
0
0
0
0
25
25
% I
% Lys:
0
13
0
25
38
13
0
0
13
0
0
0
0
0
0
% K
% Leu:
25
0
0
0
0
13
0
25
13
0
0
13
25
13
0
% L
% Met:
0
0
13
0
0
0
0
0
0
0
0
0
13
0
0
% M
% Asn:
0
0
0
0
0
13
0
0
0
0
25
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
13
0
13
0
0
0
0
0
0
% P
% Gln:
0
0
13
0
0
0
13
0
13
0
0
0
0
0
13
% Q
% Arg:
25
38
13
25
0
0
0
0
0
0
0
13
25
0
0
% R
% Ser:
25
0
0
0
13
13
0
50
13
0
0
0
0
0
38
% S
% Thr:
0
13
0
0
0
0
0
0
13
0
0
25
13
0
0
% T
% Val:
0
0
0
0
0
13
0
0
0
0
13
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
13
0
0
0
0
0
0
0
38
0
25
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _