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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC46
All Species:
3.33
Human Site:
S249
Identified Species:
8.15
UniProt:
Q96FV0
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96FV0
NP_219481.1
321
35340
S249
V
P
M
A
G
D
S
S
P
S
A
T
P
A
Q
Chimpanzee
Pan troglodytes
XP_523819
214
23305
P143
P
M
A
G
D
S
S
P
S
A
T
P
A
Q
G
Rhesus Macaque
Macaca mulatta
XP_001112935
112
12750
Q41
L
Q
G
N
K
I
Q
Q
I
E
N
L
A
C
V
Dog
Lupus familis
XP_537660
322
35924
S251
E
P
M
A
R
D
S
S
P
S
V
T
P
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9DAP0
323
36029
G251
L
P
A
V
P
M
A
G
D
C
S
S
T
A
T
Rat
Rattus norvegicus
Q6AXZ2
323
35984
G251
L
P
A
V
P
M
A
G
D
C
S
P
A
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510631
302
33003
A230
S
Q
H
V
A
L
M
A
T
L
P
A
P
L
D
Chicken
Gallus gallus
XP_001236149
190
21000
D119
I
E
K
I
E
N
L
D
C
F
P
N
L
Q
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q504C1
561
62597
G479
M
V
L
A
V
P
A
G
M
Y
A
C
T
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P45969
326
37341
E254
I
K
T
F
S
G
V
E
R
L
E
S
L
N
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.7
33.6
78.5
N.A.
69
71.2
N.A.
49.8
20.8
N.A.
21.3
N.A.
N.A.
N.A.
22.7
N.A.
Protein Similarity:
100
66
34.5
83.2
N.A.
78.6
79.8
N.A.
62.3
32.7
N.A.
33.5
N.A.
N.A.
N.A.
38.9
N.A.
P-Site Identity:
100
6.6
0
73.3
N.A.
13.3
6.6
N.A.
6.6
0
N.A.
13.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
13.3
6.6
73.3
N.A.
40
26.6
N.A.
13.3
13.3
N.A.
33.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
30
30
10
0
30
10
0
10
20
10
30
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
20
0
10
0
10
0
% C
% Asp:
0
0
0
0
10
20
0
10
20
0
0
0
0
0
30
% D
% Glu:
10
10
0
0
10
0
0
10
0
10
10
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
10
% F
% Gly:
0
0
10
10
10
10
0
30
0
0
0
0
0
0
10
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
20
0
0
10
0
10
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
10
10
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
30
0
10
0
0
10
10
0
0
20
0
10
20
10
0
% L
% Met:
10
10
20
0
0
20
10
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
10
0
0
0
0
10
10
0
10
0
% N
% Pro:
10
40
0
0
20
10
0
10
20
0
20
20
30
0
0
% P
% Gln:
0
20
0
0
0
0
10
10
0
0
0
0
0
20
20
% Q
% Arg:
0
0
0
0
10
0
0
0
10
0
0
0
0
10
0
% R
% Ser:
10
0
0
0
10
10
30
20
10
20
20
20
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
0
10
0
10
20
20
10
20
% T
% Val:
10
10
0
30
10
0
10
0
0
0
10
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _