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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LRRC46 All Species: 4.85
Human Site: S287 Identified Species: 11.85
UniProt: Q96FV0 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96FV0 NP_219481.1 321 35340 S287 L I P R G H Q S S F W G R K G
Chimpanzee Pan troglodytes XP_523819 214 23305 S181 I P R G H Q S S L W G R K G A
Rhesus Macaque Macaca mulatta XP_001112935 112 12750 S79 C L Q F L D L S E N L I E T L
Dog Lupus familis XP_537660 322 35924 I289 L V S S Q Q S I T Q A K K G T
Cat Felis silvestris
Mouse Mus musculus Q9DAP0 323 36029 S289 Q V S K N Q K S S V Q A R K G
Rat Rattus norvegicus Q6AXZ2 323 35984 G289 Q V P R N Q K G S V Q A R K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510631 302 33003 L268 A S P A S P N L Q G A P R K S
Chicken Gallus gallus XP_001236149 190 21000 Q157 D L S Q N Q I Q T L D A D E L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q504C1 561 62597 T517 P T G D R Q G T F D S L Q A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P45969 326 37341 N292 Q T V Y L E R N P F Y F N D T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.7 33.6 78.5 N.A. 69 71.2 N.A. 49.8 20.8 N.A. 21.3 N.A. N.A. N.A. 22.7 N.A.
Protein Similarity: 100 66 34.5 83.2 N.A. 78.6 79.8 N.A. 62.3 32.7 N.A. 33.5 N.A. N.A. N.A. 38.9 N.A.
P-Site Identity: 100 6.6 6.6 6.6 N.A. 33.3 40 N.A. 20 0 N.A. 0 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 26.6 13.3 26.6 N.A. 53.3 53.3 N.A. 20 26.6 N.A. 13.3 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 0 0 0 0 0 0 20 30 0 10 20 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 10 0 10 0 0 0 10 10 0 10 10 0 % D
% Glu: 0 0 0 0 0 10 0 0 10 0 0 0 10 10 0 % E
% Phe: 0 0 0 10 0 0 0 0 10 20 0 10 0 0 0 % F
% Gly: 0 0 10 10 10 0 10 10 0 10 10 10 0 20 30 % G
% His: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 10 0 0 0 0 10 10 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 10 0 0 20 0 0 0 0 10 20 40 0 % K
% Leu: 20 20 0 0 20 0 10 10 10 10 10 10 0 0 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 30 0 10 10 0 10 0 0 10 0 0 % N
% Pro: 10 10 30 0 0 10 0 0 10 0 0 10 0 0 0 % P
% Gln: 30 0 10 10 10 60 10 10 10 10 20 0 10 0 0 % Q
% Arg: 0 0 10 20 10 0 10 0 0 0 0 10 40 0 0 % R
% Ser: 0 10 30 10 10 0 20 40 30 0 10 0 0 0 10 % S
% Thr: 0 20 0 0 0 0 0 10 20 0 0 0 0 10 20 % T
% Val: 0 30 10 0 0 0 0 0 0 20 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _