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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC1
All Species:
17.88
Human Site:
S43
Identified Species:
32.78
UniProt:
Q96FV9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96FV9
NP_005122.2
657
75666
S43
T
F
S
Q
V
P
G
S
E
N
E
K
K
C
T
Chimpanzee
Pan troglodytes
XP_512049
657
75660
S43
T
F
S
Q
V
P
G
S
E
N
E
K
K
C
T
Rhesus Macaque
Macaca mulatta
XP_001090085
657
75646
S43
T
F
S
Q
V
P
G
S
E
N
E
K
K
C
T
Dog
Lupus familis
XP_547651
657
75635
S43
T
F
S
Q
L
P
G
S
E
N
E
K
K
C
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3N6
657
75417
S43
A
F
S
Q
L
P
G
S
E
N
E
K
K
C
T
Rat
Rattus norvegicus
P59924
343
40225
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521474
311
36295
Chicken
Gallus gallus
XP_419149
540
62567
Frog
Xenopus laevis
NP_001082490
654
74928
N43
S
Q
L
P
G
S
E
N
E
K
K
L
A
L
D
Zebra Danio
Brachydanio rerio
NP_958481
655
74980
E45
H
L
P
G
N
E
T
E
K
K
A
T
L
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649594
701
80742
N51
E
Y
N
R
F
P
A
N
T
E
H
D
K
R
L
Honey Bee
Apis mellifera
XP_393145
655
76230
A43
T
N
D
S
D
R
K
A
A
I
D
Q
A
L
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793772
628
72543
F45
Q
L
F
L
A
R
F
F
P
L
D
E
K
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.5
98.4
N.A.
96.1
39.4
N.A.
41.8
74.2
80
75
N.A.
36.6
45.2
N.A.
41.2
Protein Similarity:
100
100
100
99.6
N.A.
98.6
44.9
N.A.
44.4
78.3
89
86.9
N.A.
54.2
62.8
N.A.
57.3
P-Site Identity:
100
100
100
93.3
N.A.
86.6
0
N.A.
0
0
6.6
0
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
0
N.A.
0
0
26.6
6.6
N.A.
40
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
8
8
8
0
8
0
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
39
0
% C
% Asp:
0
0
8
0
8
0
0
0
0
0
16
8
0
8
8
% D
% Glu:
8
0
0
0
0
8
8
8
47
8
39
8
0
0
0
% E
% Phe:
0
39
8
0
8
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
0
39
0
0
0
0
0
0
0
8
% G
% His:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
8
16
8
39
54
0
0
% K
% Leu:
0
16
8
8
16
0
0
0
0
8
0
8
8
16
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
8
0
0
16
0
39
0
0
0
0
0
% N
% Pro:
0
0
8
8
0
47
0
0
8
0
0
0
0
0
0
% P
% Gln:
8
8
0
39
0
0
0
0
0
0
0
8
0
0
8
% Q
% Arg:
0
0
0
8
0
16
0
0
0
0
0
0
0
8
8
% R
% Ser:
8
0
39
8
0
8
0
39
0
0
0
0
0
8
0
% S
% Thr:
39
0
0
0
0
0
8
0
8
0
0
8
0
0
39
% T
% Val:
0
0
0
0
24
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _