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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC1
All Species:
19.09
Human Site:
S560
Identified Species:
35
UniProt:
Q96FV9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96FV9
NP_005122.2
657
75666
S560
A
L
L
K
E
N
E
S
P
D
V
R
R
D
K
Chimpanzee
Pan troglodytes
XP_512049
657
75660
S560
A
L
L
K
E
N
E
S
P
D
V
R
R
D
K
Rhesus Macaque
Macaca mulatta
XP_001090085
657
75646
S560
A
L
L
K
E
N
E
S
P
D
V
R
R
D
K
Dog
Lupus familis
XP_547651
657
75635
S560
A
L
L
K
E
N
E
S
P
D
V
R
R
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3N6
657
75417
S560
A
L
L
K
E
N
E
S
P
D
V
R
R
D
K
Rat
Rattus norvegicus
P59924
343
40225
E261
S
L
T
N
K
L
D
E
Q
W
K
I
L
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521474
311
36295
S228
E
Y
K
A
V
N
N
S
N
Y
G
W
R
A
L
Chicken
Gallus gallus
XP_419149
540
62567
M457
K
P
M
T
G
E
Q
M
E
A
F
A
I
R
L
Frog
Xenopus laevis
NP_001082490
654
74928
E555
S
L
L
K
E
N
N
E
S
P
A
E
E
Q
Q
Zebra Danio
Brachydanio rerio
NP_958481
655
74980
D563
N
L
L
K
D
S
N
D
S
P
S
I
Q
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649594
701
80742
V595
V
V
E
E
V
D
E
V
P
A
H
E
K
P
L
Honey Bee
Apis mellifera
XP_393145
655
76230
D551
N
D
Q
E
F
N
E
D
V
L
K
Q
D
N
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793772
628
72543
V541
L
G
F
S
D
D
E
V
T
A
I
L
S
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.5
98.4
N.A.
96.1
39.4
N.A.
41.8
74.2
80
75
N.A.
36.6
45.2
N.A.
41.2
Protein Similarity:
100
100
100
99.6
N.A.
98.6
44.9
N.A.
44.4
78.3
89
86.9
N.A.
54.2
62.8
N.A.
57.3
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
20
0
33.3
26.6
N.A.
13.3
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
20
13.3
46.6
46.6
N.A.
40
40
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
0
0
8
0
0
0
0
0
24
8
8
0
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
16
16
8
16
0
39
0
0
8
39
0
% D
% Glu:
8
0
8
16
47
8
62
16
8
0
0
16
8
8
8
% E
% Phe:
0
0
8
0
8
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
8
0
0
8
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
16
8
0
0
% I
% Lys:
8
0
8
54
8
0
0
0
0
0
16
0
8
0
47
% K
% Leu:
8
62
54
0
0
8
0
0
0
8
0
8
8
0
24
% L
% Met:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
16
0
0
8
0
62
24
0
8
0
0
0
0
8
0
% N
% Pro:
0
8
0
0
0
0
0
0
47
16
0
0
0
8
8
% P
% Gln:
0
0
8
0
0
0
8
0
8
0
0
8
8
8
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
39
47
8
0
% R
% Ser:
16
0
0
8
0
8
0
47
16
0
8
0
8
8
0
% S
% Thr:
0
0
8
8
0
0
0
0
8
0
0
0
0
0
8
% T
% Val:
8
8
0
0
16
0
0
16
8
0
39
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _