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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC1
All Species:
26.97
Human Site:
T127
Identified Species:
49.44
UniProt:
Q96FV9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96FV9
NP_005122.2
657
75666
T127
V
A
T
W
K
S
N
T
F
Y
S
A
G
K
N
Chimpanzee
Pan troglodytes
XP_512049
657
75660
T127
V
A
T
W
K
S
N
T
F
Y
S
A
G
K
N
Rhesus Macaque
Macaca mulatta
XP_001090085
657
75646
T127
V
A
T
W
K
S
N
T
F
Y
S
A
G
K
N
Dog
Lupus familis
XP_547651
657
75635
T127
V
A
T
W
K
S
N
T
F
Y
S
A
G
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3N6
657
75417
T127
V
A
T
W
K
S
N
T
F
Y
S
A
G
K
N
Rat
Rattus norvegicus
P59924
343
40225
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521474
311
36295
Chicken
Gallus gallus
XP_419149
540
62567
L43
F
L
A
R
L
F
P
L
S
E
K
S
G
L
N
Frog
Xenopus laevis
NP_001082490
654
74928
T125
V
G
T
W
K
S
N
T
F
Y
S
A
G
K
N
Zebra Danio
Brachydanio rerio
NP_958481
655
74980
T127
V
S
T
W
K
S
N
T
F
Y
S
A
G
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649594
701
80742
I134
V
E
V
W
K
E
E
I
F
F
S
S
C
K
N
Honey Bee
Apis mellifera
XP_393145
655
76230
L123
V
V
V
W
K
E
D
L
F
F
S
A
C
K
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793772
628
72543
E125
P
L
Q
C
Y
T
K
E
K
W
K
D
F
S
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.5
98.4
N.A.
96.1
39.4
N.A.
41.8
74.2
80
75
N.A.
36.6
45.2
N.A.
41.2
Protein Similarity:
100
100
100
99.6
N.A.
98.6
44.9
N.A.
44.4
78.3
89
86.9
N.A.
54.2
62.8
N.A.
57.3
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
0
13.3
93.3
93.3
N.A.
46.6
53.3
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
0
20
93.3
100
N.A.
60
66.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
39
8
0
0
0
0
0
0
0
0
62
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
16
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% D
% Glu:
0
8
0
0
0
16
8
8
0
8
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
8
0
0
70
16
0
0
8
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
62
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
70
0
8
0
8
0
16
0
0
70
0
% K
% Leu:
0
16
0
0
8
0
0
16
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
54
0
0
0
0
0
0
0
85
% N
% Pro:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
54
0
0
8
0
70
16
0
8
0
% S
% Thr:
0
0
54
0
0
8
0
54
0
0
0
0
0
0
0
% T
% Val:
70
8
16
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
70
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
54
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _