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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC1
All Species:
30.61
Human Site:
T439
Identified Species:
56.11
UniProt:
Q96FV9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96FV9
NP_005122.2
657
75666
T439
L
M
G
N
E
E
L
T
R
L
W
N
L
C
P
Chimpanzee
Pan troglodytes
XP_512049
657
75660
T439
L
M
G
N
E
E
L
T
R
L
W
N
L
C
P
Rhesus Macaque
Macaca mulatta
XP_001090085
657
75646
T439
L
M
G
N
E
E
L
T
R
L
W
N
L
C
P
Dog
Lupus familis
XP_547651
657
75635
T439
L
M
G
N
E
E
L
T
R
L
W
N
L
C
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3N6
657
75417
T439
L
I
G
N
E
E
L
T
R
L
W
N
L
C
P
Rat
Rattus norvegicus
P59924
343
40225
Q151
F
F
E
E
A
I
E
Q
A
D
A
E
N
M
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521474
311
36295
H118
R
F
S
K
M
V
E
H
I
L
N
T
E
E
N
Chicken
Gallus gallus
XP_419149
540
62567
E347
E
Y
M
P
T
L
E
E
F
F
E
E
A
I
E
Frog
Xenopus laevis
NP_001082490
654
74928
T436
S
L
G
N
D
E
L
T
R
L
W
N
L
C
P
Zebra Danio
Brachydanio rerio
NP_958481
655
74980
T440
L
M
G
N
D
E
L
T
R
L
W
N
L
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649594
701
80742
L449
S
R
S
G
K
F
Y
L
G
N
D
N
L
T
R
Honey Bee
Apis mellifera
XP_393145
655
76230
T430
H
M
G
N
P
E
L
T
K
L
W
N
L
C
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793772
628
72543
Q431
N
N
S
N
Y
A
W
Q
A
I
R
L
L
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.5
98.4
N.A.
96.1
39.4
N.A.
41.8
74.2
80
75
N.A.
36.6
45.2
N.A.
41.2
Protein Similarity:
100
100
100
99.6
N.A.
98.6
44.9
N.A.
44.4
78.3
89
86.9
N.A.
54.2
62.8
N.A.
57.3
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
6.6
0
80
86.6
N.A.
13.3
80
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
6.6
0
93.3
93.3
N.A.
20
86.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
0
16
0
8
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
54
0
% C
% Asp:
0
0
0
0
16
0
0
0
0
8
8
0
0
0
0
% D
% Glu:
8
0
8
8
39
62
24
8
0
0
8
16
8
8
8
% E
% Phe:
8
16
0
0
0
8
0
0
8
8
0
0
0
0
0
% F
% Gly:
0
0
62
8
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
8
0
0
8
8
0
0
0
8
0
% I
% Lys:
0
0
0
8
8
0
0
0
8
0
0
0
0
0
8
% K
% Leu:
47
8
0
0
0
8
62
8
0
70
0
8
77
0
0
% L
% Met:
0
47
8
0
8
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
8
0
70
0
0
0
0
0
8
8
70
8
8
8
% N
% Pro:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
62
% P
% Gln:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% Q
% Arg:
8
8
0
0
0
0
0
0
54
0
8
0
0
0
8
% R
% Ser:
16
0
24
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
62
0
0
0
8
0
8
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
62
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _