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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: THOC1 All Species: 27.88
Human Site: T542 Identified Species: 51.11
UniProt: Q96FV9 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96FV9 NP_005122.2 657 75666 T542 P P S E E I K T G E D E D E E
Chimpanzee Pan troglodytes XP_512049 657 75660 T542 P P S E E I K T G E D E D E E
Rhesus Macaque Macaca mulatta XP_001090085 657 75646 T542 P P S E E I K T G E D E D E E
Dog Lupus familis XP_547651 657 75635 T542 P P S E E I K T G E D E D E E
Cat Felis silvestris
Mouse Mus musculus Q8R3N6 657 75417 T542 P P S E E I K T G E D E D E E
Rat Rattus norvegicus P59924 343 40225 P246 P D V R Q D K P I T G E R I E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521474 311 36295 D213 E E A I E Q A D P E N M V E N
Chicken Gallus gallus XP_419149 540 62567 E442 A L L K E N N E S P E V Q R D
Frog Xenopus laevis NP_001082490 654 74928 T539 P P S E E I K T V D E D E D N
Zebra Danio Brachydanio rerio NP_958481 655 74980 T545 I P S E E I K T G E E D D D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649594 701 80742 P576 V A L Q D G E P E Q D L E V E
Honey Bee Apis mellifera XP_393145 655 76230 L533 Q T Q S D I K L E T E E T P P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793772 628 72543 S526 V A S K I G D S W Q T L A V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.5 98.4 N.A. 96.1 39.4 N.A. 41.8 74.2 80 75 N.A. 36.6 45.2 N.A. 41.2
Protein Similarity: 100 100 100 99.6 N.A. 98.6 44.9 N.A. 44.4 78.3 89 86.9 N.A. 54.2 62.8 N.A. 57.3
P-Site Identity: 100 100 100 100 N.A. 100 26.6 N.A. 20 6.6 53.3 73.3 N.A. 13.3 20 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 33.3 N.A. 33.3 26.6 86.6 93.3 N.A. 46.6 33.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 16 8 0 0 0 8 0 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 16 8 8 8 0 8 47 16 47 16 8 % D
% Glu: 8 8 0 54 70 0 8 8 16 54 31 54 16 47 70 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 16 0 0 47 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 8 8 62 0 0 8 0 0 0 0 8 0 % I
% Lys: 0 0 0 16 0 0 70 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 16 0 0 0 0 8 0 0 0 16 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 8 8 0 0 0 8 0 0 0 16 % N
% Pro: 54 54 0 0 0 0 0 16 8 8 0 0 0 8 8 % P
% Gln: 8 0 8 8 8 8 0 0 0 16 0 0 8 0 0 % Q
% Arg: 0 0 0 8 0 0 0 0 0 0 0 0 8 8 0 % R
% Ser: 0 0 62 8 0 0 0 8 8 0 0 0 0 0 0 % S
% Thr: 0 8 0 0 0 0 0 54 0 16 8 0 8 0 0 % T
% Val: 16 0 8 0 0 0 0 0 8 0 0 8 8 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _