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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC1
All Species:
21.82
Human Site:
Y591
Identified Species:
40
UniProt:
Q96FV9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96FV9
NP_005122.2
657
75666
Y591
Q
W
K
I
L
A
P
Y
L
E
M
K
D
S
E
Chimpanzee
Pan troglodytes
XP_512049
657
75660
Y591
Q
W
K
I
L
A
P
Y
L
E
M
K
D
S
E
Rhesus Macaque
Macaca mulatta
XP_001090085
657
75646
Y591
Q
W
K
I
L
A
P
Y
L
E
M
K
D
S
E
Dog
Lupus familis
XP_547651
657
75635
Y591
Q
W
K
I
L
A
P
Y
L
E
M
K
D
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3N6
657
75417
Y591
Q
W
K
I
L
A
P
Y
L
E
I
K
D
S
D
Rat
Rattus norvegicus
P59924
343
40225
D286
Q
I
E
C
Y
S
E
D
M
K
K
R
A
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521474
311
36295
F253
F
Q
P
T
N
Q
Q
F
K
S
L
P
E
Y
L
Chicken
Gallus gallus
XP_419149
540
62567
I482
L
E
M
K
D
S
D
I
R
Q
I
E
A
D
S
Frog
Xenopus laevis
NP_001082490
654
74928
Y588
H
W
K
T
L
A
P
Y
L
D
M
K
D
L
D
Zebra Danio
Brachydanio rerio
NP_958481
655
74980
H594
Q
W
K
T
L
A
D
H
L
E
M
S
D
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649594
701
80742
N631
G
K
K
I
G
F
T
N
D
E
L
L
F
F
Q
Honey Bee
Apis mellifera
XP_393145
655
76230
L583
T
P
E
M
V
A
R
L
S
E
I
L
K
N
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793772
628
72543
A568
Q
W
Q
D
K
E
G
A
E
P
S
R
E
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.5
98.4
N.A.
96.1
39.4
N.A.
41.8
74.2
80
75
N.A.
36.6
45.2
N.A.
41.2
Protein Similarity:
100
100
100
99.6
N.A.
98.6
44.9
N.A.
44.4
78.3
89
86.9
N.A.
54.2
62.8
N.A.
57.3
P-Site Identity:
100
100
100
100
N.A.
86.6
6.6
N.A.
0
0
66.6
66.6
N.A.
20
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
20
26.6
80
73.3
N.A.
33.3
53.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
62
0
8
0
0
0
0
16
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
0
16
8
8
8
0
0
54
8
24
% D
% Glu:
0
8
16
0
0
8
8
0
8
62
0
8
16
0
39
% E
% Phe:
8
0
0
0
0
8
0
8
0
0
0
0
8
8
0
% F
% Gly:
8
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
47
0
0
0
8
0
0
24
0
0
0
0
% I
% Lys:
0
8
62
8
8
0
0
0
8
8
8
47
8
16
0
% K
% Leu:
8
0
0
0
54
0
0
8
54
0
16
16
0
8
16
% L
% Met:
0
0
8
8
0
0
0
0
8
0
47
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
8
0
0
0
0
0
8
0
% N
% Pro:
0
8
8
0
0
0
47
0
0
8
0
8
0
0
0
% P
% Gln:
62
8
8
0
0
8
8
0
0
8
0
0
0
0
16
% Q
% Arg:
0
0
0
0
0
0
8
0
8
0
0
16
0
0
0
% R
% Ser:
0
0
0
0
0
16
0
0
8
8
8
8
0
39
8
% S
% Thr:
8
0
0
24
0
0
8
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
62
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
47
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _