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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OTUB1 All Species: 22.42
Human Site: S127 Identified Species: 41.11
UniProt: Q96FW1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96FW1 NP_060140.2 271 31284 S127 K S K E D L V S Q G F T E F T
Chimpanzee Pan troglodytes XP_001162994 250 29049 G108 K E D L V S Q G F T E F T I E
Rhesus Macaque Macaca mulatta XP_001115486 274 31487 S130 K S K E D L V S Q G F T E F T
Dog Lupus familis XP_533248 279 32113 S135 K S K E D L V S Q G F T E F T
Cat Felis silvestris
Mouse Mus musculus Q7TQI3 271 31252 S127 K S K E D L V S Q G F T E F T
Rat Rattus norvegicus XP_234947 269 31060 S125 K S K E D L V S Q G F T E F T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001089759 268 30824 R123 H S K D E L I R Q G F T E F T
Zebra Danio Brachydanio rerio NP_001002411 267 30783 S123 K S K L D L V S Q G F T E F T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VL00 262 30354 Q111 E S K E K L V Q L G F P S F T
Honey Bee Apis mellifera XP_001120477 234 27018 P92 N L V A L G F P Q F T V E D F
Nematode Worm Caenorhab. elegans Q9XVR6 284 32275 E124 D W T R T L V E L G F P D W T
Sea Urchin Strong. purpuratus XP_791493 267 30648 L123 K S K E E L I L L G F P A F T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LG98 306 34416 L128 V E K C R K T L Q N L G Y T D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.1 93 97.1 N.A. 99.6 95.1 N.A. N.A. N.A. 74.9 79.3 N.A. 53.8 49.8 32.7 54.9
Protein Similarity: 100 90.7 94.5 97.1 N.A. 100 97.4 N.A. N.A. N.A. 88.1 88.1 N.A. 71.5 67.9 54.5 70.4
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. N.A. N.A. 66.6 93.3 N.A. 60 13.3 33.3 60
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. N.A. N.A. 86.6 93.3 N.A. 66.6 13.3 46.6 73.3
Percent
Protein Identity: N.A. N.A. N.A. 36.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 54.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 8 47 0 0 0 0 0 0 0 8 8 8 % D
% Glu: 8 16 0 54 16 0 0 8 0 0 8 0 62 0 8 % E
% Phe: 0 0 0 0 0 0 8 0 8 8 77 8 0 70 8 % F
% Gly: 0 0 0 0 0 8 0 8 0 77 0 8 0 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 16 0 0 0 0 0 0 8 0 % I
% Lys: 62 0 77 0 8 8 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 0 16 8 77 0 16 24 0 8 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 8 0 0 0 24 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 8 70 0 0 0 0 0 0 % Q
% Arg: 0 0 0 8 8 0 0 8 0 0 0 0 0 0 0 % R
% Ser: 0 70 0 0 0 8 0 47 0 0 0 0 8 0 0 % S
% Thr: 0 0 8 0 8 0 8 0 0 8 8 54 8 8 77 % T
% Val: 8 0 8 0 8 0 62 0 0 0 0 8 0 0 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _