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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OTUB1 All Species: 24.24
Human Site: S154 Identified Species: 44.44
UniProt: Q96FW1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96FW1 NP_060140.2 271 31284 S154 E Q V E K Q T S V A D L L A S
Chimpanzee Pan troglodytes XP_001162994 250 29049 A135 V E K Q T S V A D L L A S F N
Rhesus Macaque Macaca mulatta XP_001115486 274 31487 S157 E Q V E K Q T S V A D L L A S
Dog Lupus familis XP_533248 279 32113 S162 E Q V E K Q T S V A D L L A S
Cat Felis silvestris
Mouse Mus musculus Q7TQI3 271 31252 S154 E Q V E K Q T S V A D L L A S
Rat Rattus norvegicus XP_234947 269 31060 S152 E Q V E K Q T S V A D L L A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001089759 268 30824 A150 A L V E K H P A V P E L L A A
Zebra Danio Brachydanio rerio NP_001002411 267 30783 S150 E A C D K Q T S V G E L L T S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VL00 262 30354 A138 Q R V S P D N A G G H S T V Q
Honey Bee Apis mellifera XP_001120477 234 27018 I119 E D A E S S Y I E L H K L F N
Nematode Worm Caenorhab. elegans Q9XVR6 284 32275 H151 E K I H S G V H T E E A V Y T
Sea Urchin Strong. purpuratus XP_791493 267 30648 S150 R S I Q D K P S L E N L V E T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LG98 306 34416 G155 Q L D D I L Q G T E E S I S Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.1 93 97.1 N.A. 99.6 95.1 N.A. N.A. N.A. 74.9 79.3 N.A. 53.8 49.8 32.7 54.9
Protein Similarity: 100 90.7 94.5 97.1 N.A. 100 97.4 N.A. N.A. N.A. 88.1 88.1 N.A. 71.5 67.9 54.5 70.4
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. N.A. N.A. 46.6 60 N.A. 6.6 20 6.6 13.3
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. N.A. N.A. 66.6 73.3 N.A. 26.6 26.6 40 60
Percent
Protein Identity: N.A. N.A. N.A. 36.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 54.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 0 0 0 0 24 0 39 0 16 0 47 8 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 16 8 8 0 0 8 0 39 0 0 0 0 % D
% Glu: 62 8 0 54 0 0 0 0 8 24 31 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 0 % F
% Gly: 0 0 0 0 0 8 0 8 8 16 0 0 0 0 0 % G
% His: 0 0 0 8 0 8 0 8 0 0 16 0 0 0 0 % H
% Ile: 0 0 16 0 8 0 0 8 0 0 0 0 8 0 0 % I
% Lys: 0 8 8 0 54 8 0 0 0 0 0 8 0 0 0 % K
% Leu: 0 16 0 0 0 8 0 0 8 16 8 62 62 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 16 % N
% Pro: 0 0 0 0 8 0 16 0 0 8 0 0 0 0 0 % P
% Gln: 16 39 0 16 0 47 8 0 0 0 0 0 0 0 8 % Q
% Arg: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 0 8 16 16 0 54 0 0 0 16 8 8 47 % S
% Thr: 0 0 0 0 8 0 47 0 16 0 0 0 8 8 16 % T
% Val: 8 0 54 0 0 0 16 0 54 0 0 0 16 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _