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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PERP All Species: 20.61
Human Site: S46 Identified Species: 45.33
UniProt: Q96FX8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96FX8 NP_071404.2 193 21386 S46 S D H G Q T S S L W W K C S Q
Chimpanzee Pan troglodytes XP_001168787 184 20535 S46 S D H V Q T S S L W W R C F L
Rhesus Macaque Macaca mulatta XP_001095578 193 21384 S46 S S H M Q T S S L W W K C S Q
Dog Lupus familis XP_533423 193 21465 S46 S D H V Q T S S L W W R C S Q
Cat Felis silvestris
Mouse Mus musculus Q9JK95 193 21549 S46 S N H I Q T S S L W W R C F D
Rat Rattus norvegicus NP_001099735 193 21584 S46 S N H I Q T S S L W W R C F D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509348 188 20829 P41 M I K T Q L L P P S K K Y W S
Chicken Gallus gallus XP_419720 189 21067 H45 S Q T L P Y V H Q A S L W E S
Frog Xenopus laevis Q6IP19 179 19823 N48 P A W V T A D N Q Y Y L S L W
Zebra Danio Brachydanio rerio Q6PFT6 181 19928 S40 L D V G A V L S P A W V T A D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782194 242 26220 A77 L G V F M R C A E I F R A I Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.3 98.4 96.3 N.A. 90.6 92.7 N.A. 64.7 52.8 30.5 30.5 N.A. N.A. N.A. N.A. 20.2
Protein Similarity: 100 85.4 98.4 98.4 N.A. 94.3 96.3 N.A. 69.4 66.8 47.6 46.6 N.A. N.A. N.A. N.A. 37.6
P-Site Identity: 100 73.3 86.6 86.6 N.A. 66.6 66.6 N.A. 13.3 6.6 0 26.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 80 86.6 93.3 N.A. 80 80 N.A. 13.3 6.6 20 33.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 10 10 0 10 0 19 0 0 10 10 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 55 0 0 % C
% Asp: 0 37 0 0 0 0 10 0 0 0 0 0 0 0 28 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 10 0 0 28 0 % F
% Gly: 0 10 0 19 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 55 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 19 0 0 0 0 0 10 0 0 0 10 0 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 10 28 0 0 0 % K
% Leu: 19 0 0 10 0 10 19 0 55 0 0 19 0 10 10 % L
% Met: 10 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 19 0 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 0 10 0 0 10 19 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 64 0 0 0 19 0 0 0 0 0 37 % Q
% Arg: 0 0 0 0 0 10 0 0 0 0 0 46 0 0 0 % R
% Ser: 64 10 0 0 0 0 55 64 0 10 10 0 10 28 19 % S
% Thr: 0 0 10 10 10 55 0 0 0 0 0 0 10 0 0 % T
% Val: 0 0 19 28 0 10 10 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 55 64 0 10 10 10 % W
% Tyr: 0 0 0 0 0 10 0 0 0 10 10 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _