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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PERP All Species: 23.33
Human Site: S58 Identified Species: 51.33
UniProt: Q96FX8 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96FX8 NP_071404.2 193 21386 S58 C S Q E G G G S G S Y E E G C
Chimpanzee Pan troglodytes XP_001168787 184 20535 S58 C F L D G C H S L M E Y A W G
Rhesus Macaque Macaca mulatta XP_001095578 193 21384 S58 C S Q E G G G S G S Y E E G C
Dog Lupus familis XP_533423 193 21465 S58 C S Q E G G G S G S Y E E G C
Cat Felis silvestris
Mouse Mus musculus Q9JK95 193 21549 S58 C F D E G G G S G S Y D D G C
Rat Rattus norvegicus NP_001099735 193 21584 S58 C F D E G G G S G S Y D D G C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509348 188 20829 T53 Y W S E T G G T G S Y E E N C
Chicken Gallus gallus XP_419720 189 21067 P57 W E S C T R P P Q G G E W N C
Frog Xenopus laevis Q6IP19 179 19823 K60 S L W E S C K K S E N R W I C
Zebra Danio Brachydanio rerio Q6PFT6 181 19928 L52 T A D D Q Y H L S L W K S C S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782194 242 26220 S89 A I Q S E G G S T S N Q V E C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.3 98.4 96.3 N.A. 90.6 92.7 N.A. 64.7 52.8 30.5 30.5 N.A. N.A. N.A. N.A. 20.2
Protein Similarity: 100 85.4 98.4 98.4 N.A. 94.3 96.3 N.A. 69.4 66.8 47.6 46.6 N.A. N.A. N.A. N.A. 37.6
P-Site Identity: 100 20 100 100 N.A. 73.3 73.3 N.A. 60 13.3 13.3 0 N.A. N.A. N.A. N.A. 40
P-Site Similarity: 100 26.6 100 100 N.A. 86.6 86.6 N.A. 66.6 13.3 13.3 26.6 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % A
% Cys: 55 0 0 10 0 19 0 0 0 0 0 0 0 10 82 % C
% Asp: 0 0 28 19 0 0 0 0 0 0 0 19 19 0 0 % D
% Glu: 0 10 0 64 10 0 0 0 0 10 10 46 37 10 0 % E
% Phe: 0 28 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 55 64 64 0 55 10 10 0 0 46 10 % G
% His: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 10 10 0 0 0 10 0 0 0 % K
% Leu: 0 10 10 0 0 0 0 10 10 10 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 19 0 0 19 0 % N
% Pro: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 37 0 10 0 0 0 10 0 0 10 0 0 0 % Q
% Arg: 0 0 0 0 0 10 0 0 0 0 0 10 0 0 0 % R
% Ser: 10 28 19 10 10 0 0 64 19 64 0 0 10 0 10 % S
% Thr: 10 0 0 0 19 0 0 10 10 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % V
% Trp: 10 10 10 0 0 0 0 0 0 0 10 0 19 10 0 % W
% Tyr: 10 0 0 0 0 10 0 0 0 0 55 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _