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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C3orf37 All Species: 24.55
Human Site: S281 Identified Species: 36
UniProt: Q96FZ2 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96FZ2 NP_001006109.1 354 40575 S281 V K K E L R A S G S S Q R M L
Chimpanzee Pan troglodytes XP_001141564 354 40530 S281 V K K E L K A S G S S Q R M L
Rhesus Macaque Macaca mulatta XP_001095849 354 40510 S281 V K K E L K A S G S S Q R M L
Dog Lupus familis XP_541742 357 40852 S280 V K K D L K A S G S S Q K M M
Cat Felis silvestris
Mouse Mus musculus Q8R1M0 353 40150 N280 V K K E P K A N G S S Q R M M
Rat Rattus norvegicus Q5XIJ1 353 40204 S280 V K K E P K A S G S S Q R M M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506143 341 39169 S276 L K K E P K M S S S G Q K M L
Chicken Gallus gallus Q5ZJT1 336 38203 V270 E L G V P K E V K A T A S S K
Frog Xenopus laevis Q6IND6 336 38261 P271 I L T Q K K G P A L S A S S K
Zebra Danio Brachydanio rerio NP_001092888 353 40019 S288 V D P T I K K S T K P T A S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649862 368 42463 P295 L A A K P A K P P M N K T M M
Honey Bee Apis mellifera XP_001121228 278 31938 F213 L H N R V P I F L N K E Q D S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202069 381 42242 S297 P E K P K A E S K S S Q F M S
Poplar Tree Populus trichocarpa XP_002303080 367 41574 P292 S E E K L E T P C S A K T V D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_180215 487 55076 N405 A V E D I P G N E N Q K T V L
Baker's Yeast Sacchar. cerevisiae Q04471 368 42883 Q297 K G E D V F N Q K K S L K R N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 98.5 86.8 N.A. 83.9 83.3 N.A. 75.1 59.8 61.8 52.5 N.A. 30.9 31 N.A. 37.5
Protein Similarity: 100 99.7 99.1 93.5 N.A. 92.9 92 N.A. 84.4 74.2 76.5 69.4 N.A. 51.6 47.1 N.A. 54.3
P-Site Identity: 100 93.3 93.3 73.3 N.A. 73.3 80 N.A. 53.3 0 6.6 13.3 N.A. 6.6 0 N.A. 40
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 73.3 20 26.6 26.6 N.A. 40 33.3 N.A. 46.6
Percent
Protein Identity: 25.3 N.A. N.A. 24.4 20.1 N.A.
Protein Similarity: 42.5 N.A. N.A. 39.8 36.4 N.A.
P-Site Identity: 13.3 N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: 53.3 N.A. N.A. 53.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 0 0 13 38 0 7 7 7 13 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 7 0 19 0 0 0 0 0 0 0 0 0 7 7 % D
% Glu: 7 13 19 38 0 7 13 0 7 0 0 7 0 0 0 % E
% Phe: 0 0 0 0 0 7 0 7 0 0 0 0 7 0 0 % F
% Gly: 0 7 7 0 0 0 13 0 38 0 7 0 0 0 0 % G
% His: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 13 0 7 0 0 0 0 0 0 0 0 % I
% Lys: 7 44 50 13 13 57 13 0 19 13 7 19 19 0 13 % K
% Leu: 19 13 0 0 32 0 0 0 7 7 0 7 0 0 32 % L
% Met: 0 0 0 0 0 0 7 0 0 7 0 0 0 57 25 % M
% Asn: 0 0 7 0 0 0 7 13 0 13 7 0 0 0 7 % N
% Pro: 7 0 7 7 32 13 0 19 7 0 7 0 0 0 0 % P
% Gln: 0 0 0 7 0 0 0 7 0 0 7 50 7 0 0 % Q
% Arg: 0 0 0 7 0 7 0 0 0 0 0 0 32 7 0 % R
% Ser: 7 0 0 0 0 0 0 50 7 57 57 0 13 19 19 % S
% Thr: 0 0 7 7 0 0 7 0 7 0 7 7 19 0 0 % T
% Val: 44 7 0 7 13 0 0 7 0 0 0 0 0 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _