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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHMP6
All Species:
45.15
Human Site:
S119
Identified Species:
66.22
UniProt:
Q96FZ7
Number Species:
15
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96FZ7
NP_078867.2
201
23485
S119
N
K
M
H
Q
V
M
S
I
E
E
V
E
R
I
Chimpanzee
Pan troglodytes
XP_001152905
208
24321
S112
N
K
M
H
Q
V
M
S
I
E
E
V
E
R
I
Rhesus Macaque
Macaca mulatta
XP_001110906
257
29807
S175
N
K
M
H
Q
V
M
S
I
E
E
V
E
R
I
Dog
Lupus familis
XP_850462
476
51202
S394
K
K
M
H
Q
V
M
S
I
E
E
V
E
R
I
Cat
Felis silvestris
Mouse
Mus musculus
P0C0A3
200
23397
S119
N
K
M
H
Q
V
M
S
I
E
E
V
E
R
I
Rat
Rattus norvegicus
Q569C1
232
26305
D124
K
A
V
H
E
N
M
D
L
N
K
I
D
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514815
223
25346
S140
T
K
M
H
Q
V
M
S
L
E
E
V
E
R
I
Chicken
Gallus gallus
Q5ZL55
200
23240
S119
N
K
M
H
Q
V
M
S
I
E
E
V
E
R
I
Frog
Xenopus laevis
Q6GMA4
200
23307
S119
K
K
M
H
E
V
M
S
I
E
E
V
E
R
I
Zebra Danio
Brachydanio rerio
Q503V0
206
23961
S119
K
K
M
H
E
V
L
S
I
E
E
V
E
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726213
212
24055
D123
K
K
V
H
E
M
L
D
I
D
E
V
E
R
I
Honey Bee
Apis mellifera
XP_394359
209
24436
S120
K
K
L
H
D
L
L
S
I
D
E
I
E
K
I
Nematode Worm
Caenorhab. elegans
NP_490762
208
24111
D123
K
K
M
N
Q
L
F
D
I
D
E
I
D
R
I
Sea Urchin
Strong. purpuratus
XP_782648
206
23787
S119
K
K
M
H
Q
M
M
S
L
D
D
V
E
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FY89
216
24591
N117
K
A
I
Q
S
E
V
N
L
D
D
V
Q
K
L
Baker's Yeast
Sacchar. cerevisiae
Q04272
221
25619
S121
K
K
L
N
K
E
F
S
N
V
D
E
L
M
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.8
74.7
37.3
N.A.
92.5
24.5
N.A.
65
81.5
74.1
67.9
N.A.
50.9
46.4
45.1
57.2
Protein Similarity:
100
83.1
76.6
40.1
N.A.
96.5
50.8
N.A.
76.2
92.5
88.5
84.9
N.A.
71.2
72.2
67.7
76.7
P-Site Identity:
100
100
100
93.3
N.A.
100
13.3
N.A.
86.6
100
86.6
73.3
N.A.
53.3
46.6
46.6
60
P-Site Similarity:
100
100
100
93.3
N.A.
100
60
N.A.
93.3
100
93.3
93.3
N.A.
86.6
86.6
80
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37
29.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.3
53.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
0
19
0
32
19
0
13
7
7
% D
% Glu:
0
0
0
0
25
13
0
0
0
57
75
7
75
0
0
% E
% Phe:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
82
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
69
0
0
19
0
0
82
% I
% Lys:
63
88
0
0
7
0
0
0
0
0
7
0
0
25
0
% K
% Leu:
0
0
13
0
0
13
19
0
25
0
0
0
7
0
13
% L
% Met:
0
0
69
0
0
13
63
0
0
0
0
0
0
7
0
% M
% Asn:
32
0
0
13
0
7
0
7
7
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
57
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
63
0
% R
% Ser:
0
0
0
0
7
0
0
75
0
0
0
0
0
0
0
% S
% Thr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
13
0
0
57
7
0
0
7
0
75
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _