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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHMP6 All Species: 26.06
Human Site: S147 Identified Species: 38.22
UniProt: Q96FZ7 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96FZ7 NP_078867.2 201 23485 S147 I D E L L A G S F T Q E D E D
Chimpanzee Pan troglodytes XP_001152905 208 24321 S140 I D E L L A G S F T Q E D E D
Rhesus Macaque Macaca mulatta XP_001110906 257 29807 S203 I D E L L A G S F T Q E D E D
Dog Lupus familis XP_850462 476 51202 S422 I D E L L A G S F T Q E D E D
Cat Felis silvestris
Mouse Mus musculus P0C0A3 200 23397 N147 I D E L L A G N F T Q E D E D
Rat Rattus norvegicus Q569C1 232 26305 R152 I S E A F S Q R V Q F A D G F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514815 223 25346 G168 I D E L L A G G S F T Q E D E
Chicken Gallus gallus Q5ZL55 200 23240 S147 I D E I L A G S L T E E D E D
Frog Xenopus laevis Q6GMA4 200 23307 S147 I D E M L S G S L T A E D E E
Zebra Danio Brachydanio rerio Q503V0 206 23961 S147 I D E M L A G S L T Q E D E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_726213 212 24055 V151 I D A I L T D V L T T Q D E E
Honey Bee Apis mellifera XP_394359 209 24436 E148 I D D I L S G E L T E N D E T
Nematode Worm Caenorhab. elegans NP_490762 208 24111 Q151 I S N M L S G Q L S N T D V S
Sea Urchin Strong. purpuratus XP_782648 206 23787 G147 I D E L L A G G L T E E D E E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FY89 216 24591 K145 L S A I L G E K L S A E D E E
Baker's Yeast Sacchar. cerevisiae Q04272 221 25619 V149 E T L S R S L V G T S N Y E D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.8 74.7 37.3 N.A. 92.5 24.5 N.A. 65 81.5 74.1 67.9 N.A. 50.9 46.4 45.1 57.2
Protein Similarity: 100 83.1 76.6 40.1 N.A. 96.5 50.8 N.A. 76.2 92.5 88.5 84.9 N.A. 71.2 72.2 67.7 76.7
P-Site Identity: 100 100 100 100 N.A. 93.3 20 N.A. 46.6 80 66.6 80 N.A. 40 46.6 26.6 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 26.6 N.A. 73.3 93.3 86.6 93.3 N.A. 60 73.3 46.6 86.6
Percent
Protein Identity: N.A. N.A. N.A. 37 29.8 N.A.
Protein Similarity: N.A. N.A. N.A. 58.3 53.8 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 7 0 57 0 0 0 0 13 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 75 7 0 0 0 7 0 0 0 0 0 88 7 44 % D
% Glu: 7 0 69 0 0 0 7 7 0 0 19 63 7 82 38 % E
% Phe: 0 0 0 0 7 0 0 0 32 7 7 0 0 0 7 % F
% Gly: 0 0 0 0 0 7 75 13 7 0 0 0 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 88 0 0 25 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % K
% Leu: 7 0 7 44 88 0 7 0 50 0 0 0 0 0 0 % L
% Met: 0 0 0 19 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 0 0 0 0 7 0 0 7 13 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 7 7 0 7 38 13 0 0 0 % Q
% Arg: 0 0 0 0 7 0 0 7 0 0 0 0 0 0 0 % R
% Ser: 0 19 0 7 0 32 0 44 7 13 7 0 0 0 7 % S
% Thr: 0 7 0 0 0 7 0 0 0 75 13 7 0 0 7 % T
% Val: 0 0 0 0 0 0 0 13 7 0 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _