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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHMP6 All Species: 55.15
Human Site: T130 Identified Species: 80.89
UniProt: Q96FZ7 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96FZ7 NP_078867.2 201 23485 T130 V E R I L D E T Q E A V E Y Q
Chimpanzee Pan troglodytes XP_001152905 208 24321 T123 V E R I L E E T Q E A V E Y Q
Rhesus Macaque Macaca mulatta XP_001110906 257 29807 T186 V E R I L D E T Q E A V E Y Q
Dog Lupus familis XP_850462 476 51202 T405 V E R I L E E T Q E A V E Y Q
Cat Felis silvestris
Mouse Mus musculus P0C0A3 200 23397 T130 V E R I L D E T Q E A V E Y Q
Rat Rattus norvegicus Q569C1 232 26305 I135 I D D L M Q D I T E Q Q D I A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514815 223 25346 T151 V E R I M D E T H D A V E Y Q
Chicken Gallus gallus Q5ZL55 200 23240 T130 V E R I I G E T Q D A V E Y Q
Frog Xenopus laevis Q6GMA4 200 23307 T130 V E R I M D E T Q E G I E Y Q
Zebra Danio Brachydanio rerio Q503V0 206 23961 T130 V E K I M D E T H D A I E Y Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_726213 212 24055 T134 V E R I M D E T R E G I E K Q
Honey Bee Apis mellifera XP_394359 209 24436 T131 I E K I M D E T R E G I E K Q
Nematode Worm Caenorhab. elegans NP_490762 208 24111 T134 I D R I M E E T K E A A E Y Q
Sea Urchin Strong. purpuratus XP_782648 206 23787 T130 V E K I M D D T R E G I E Y Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FY89 216 24591 T128 V Q K L M D D T A E A K A Y Q
Baker's Yeast Sacchar. cerevisiae Q04272 221 25619 D132 E L M D D V Q D Q I A Y Q N E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.8 74.7 37.3 N.A. 92.5 24.5 N.A. 65 81.5 74.1 67.9 N.A. 50.9 46.4 45.1 57.2
Protein Similarity: 100 83.1 76.6 40.1 N.A. 96.5 50.8 N.A. 76.2 92.5 88.5 84.9 N.A. 71.2 72.2 67.7 76.7
P-Site Identity: 100 93.3 100 93.3 N.A. 100 6.6 N.A. 80 80 80 66.6 N.A. 66.6 53.3 60 60
P-Site Similarity: 100 100 100 100 N.A. 100 46.6 N.A. 93.3 93.3 93.3 93.3 N.A. 86.6 86.6 93.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. 37 29.8 N.A.
Protein Similarity: N.A. N.A. N.A. 58.3 53.8 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 80 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 7 0 69 7 7 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 13 7 7 7 63 19 7 0 19 0 0 7 0 0 % D
% Glu: 7 75 0 0 0 19 75 0 0 75 0 0 82 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 7 0 0 0 0 25 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % H
% Ile: 19 0 0 82 7 0 0 7 0 7 0 32 0 7 0 % I
% Lys: 0 0 25 0 0 0 0 0 7 0 0 7 0 13 0 % K
% Leu: 0 7 0 13 32 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 7 0 57 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 7 0 0 0 7 7 0 50 0 7 7 7 0 88 % Q
% Arg: 0 0 63 0 0 0 0 0 19 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 88 7 0 0 0 0 0 0 % T
% Val: 75 0 0 0 0 7 0 0 0 0 0 44 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 7 0 75 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _