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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHMP6 All Species: 46.06
Human Site: T14 Identified Species: 67.56
UniProt: Q96FZ7 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96FZ7 NP_078867.2 201 23485 T14 R K K Q S R V T E Q D K A I L
Chimpanzee Pan troglodytes XP_001152905 208 24321 G11 P C P G R V A G G T W Q L K Q
Rhesus Macaque Macaca mulatta XP_001110906 257 29807 S64 R Q C R G G P S H P C D G L W
Dog Lupus familis XP_850462 476 51202 S277 Q Q H P A R D S R G R A Q I L
Cat Felis silvestris
Mouse Mus musculus P0C0A3 200 23397 T14 R K K Q S R V T E Q D R A I L
Rat Rattus norvegicus Q569C1 232 26305 S13 K F F K G S R S S R A R A A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514815 223 25346 S35 R P T I T S N S D S G R G A V
Chicken Gallus gallus Q5ZL55 200 23240 T14 R K R R S R V T E Q D K A V L
Frog Xenopus laevis Q6GMA4 200 23307 T14 R K R R S R V T E Q D K A V L
Zebra Danio Brachydanio rerio Q503V0 206 23961 T14 K K K A T R V T E Q D R A V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_726213 212 24055 T18 K T A P S R I T D Q D K A V L
Honey Bee Apis mellifera XP_394359 209 24436 T15 K K P P S R V T E Q D K A I L
Nematode Worm Caenorhab. elegans NP_490762 208 24111 S18 S P K S A P V S D Q D N A I L
Sea Urchin Strong. purpuratus XP_782648 206 23787 T14 G N K K S R V T E Q D K A V L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FY89 216 24591 T12 F V K K P K I T E V D R A I L
Baker's Yeast Sacchar. cerevisiae Q04272 221 25619 T11 K S S K V H I T K T D R A I L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.8 74.7 37.3 N.A. 92.5 24.5 N.A. 65 81.5 74.1 67.9 N.A. 50.9 46.4 45.1 57.2
Protein Similarity: 100 83.1 76.6 40.1 N.A. 96.5 50.8 N.A. 76.2 92.5 88.5 84.9 N.A. 71.2 72.2 67.7 76.7
P-Site Identity: 100 0 6.6 20 N.A. 93.3 6.6 N.A. 6.6 80 80 66.6 N.A. 53.3 80 46.6 73.3
P-Site Similarity: 100 6.6 33.3 46.6 N.A. 100 40 N.A. 40 100 100 93.3 N.A. 80 86.6 66.6 86.6
Percent
Protein Identity: N.A. N.A. N.A. 37 29.8 N.A.
Protein Similarity: N.A. N.A. N.A. 58.3 53.8 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 13 0 7 0 0 0 7 7 75 13 0 % A
% Cys: 0 7 7 0 0 0 0 0 0 0 7 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 7 0 19 0 69 7 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 % E
% Phe: 7 7 7 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 0 7 13 7 0 7 7 7 7 0 13 0 0 % G
% His: 0 0 7 0 0 7 0 0 7 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 0 19 0 0 0 0 0 0 44 0 % I
% Lys: 32 38 38 25 0 7 0 0 7 0 0 38 0 7 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 7 7 75 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 7 0 0 0 0 7 0 0 0 % N
% Pro: 7 13 13 19 7 7 7 0 0 7 0 0 0 0 7 % P
% Gln: 7 13 0 13 0 0 0 0 0 57 0 7 7 0 7 % Q
% Arg: 38 0 13 19 7 57 7 0 7 7 7 38 0 0 0 % R
% Ser: 7 7 7 7 44 13 0 32 7 7 0 0 0 0 0 % S
% Thr: 0 7 7 0 13 0 0 63 0 13 0 0 0 0 0 % T
% Val: 0 7 0 0 7 7 50 0 0 7 0 0 0 32 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 7 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _