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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHMP6 All Species: 46.97
Human Site: T77 Identified Species: 68.89
UniProt: Q96FZ7 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96FZ7 NP_078867.2 201 23485 T77 Q E Q L L D R T E N Q I S S L
Chimpanzee Pan troglodytes XP_001152905 208 24321 T70 Q E Q L L D R T E N Q I S S L
Rhesus Macaque Macaca mulatta XP_001110906 257 29807 T133 Q E Q L L D R T E N Q I S S L
Dog Lupus familis XP_850462 476 51202 T352 R E Q L L D K T E N Q I S S L
Cat Felis silvestris
Mouse Mus musculus P0C0A3 200 23397 T77 R E Q L L D R T E N Q I S S L
Rat Rattus norvegicus Q569C1 232 26305 I82 F E K Q L T Q I D G T L S T I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514815 223 25346 T98 R E Q L L D K T E T Q I T N L
Chicken Gallus gallus Q5ZL55 200 23240 T77 Q E Q L L D K T D N Q I S N L
Frog Xenopus laevis Q6GMA4 200 23307 T77 Q E Q L L E K T D N Q I S N L
Zebra Danio Brachydanio rerio Q503V0 206 23961 T77 Q D Q L L E K T E N Q I S N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_726213 212 24055 A81 Q E S L L T N A D K Q L E N L
Honey Bee Apis mellifera XP_394359 209 24436 T78 Q E Q I L S K T D G Q L E N L
Nematode Worm Caenorhab. elegans NP_490762 208 24111 T81 Q E K I I D Q T L N H L S K I
Sea Urchin Strong. purpuratus XP_782648 206 23787 T77 Q E S L L A K T D S Q L D N L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FY89 216 24591 V75 Q E E L L K Q V D Q W L I N V
Baker's Yeast Sacchar. cerevisiae Q04272 221 25619 A79 Q E H L L Q Q A S D Q L I N L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.8 74.7 37.3 N.A. 92.5 24.5 N.A. 65 81.5 74.1 67.9 N.A. 50.9 46.4 45.1 57.2
Protein Similarity: 100 83.1 76.6 40.1 N.A. 96.5 50.8 N.A. 76.2 92.5 88.5 84.9 N.A. 71.2 72.2 67.7 76.7
P-Site Identity: 100 100 100 86.6 N.A. 93.3 20 N.A. 66.6 80 73.3 73.3 N.A. 40 46.6 40 46.6
P-Site Similarity: 100 100 100 100 N.A. 100 60 N.A. 93.3 100 100 100 N.A. 60 80 80 80
Percent
Protein Identity: N.A. N.A. N.A. 37 29.8 N.A.
Protein Similarity: N.A. N.A. N.A. 58.3 53.8 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 0 13 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 50 0 0 44 7 0 0 7 0 0 % D
% Glu: 0 94 7 0 0 13 0 0 44 0 0 0 13 0 0 % E
% Phe: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % G
% His: 0 0 7 0 0 0 0 0 0 0 7 0 0 0 0 % H
% Ile: 0 0 0 13 7 0 0 7 0 0 0 57 13 0 13 % I
% Lys: 0 0 13 0 0 7 44 0 0 7 0 0 0 7 0 % K
% Leu: 0 0 0 82 94 0 0 0 7 0 0 44 0 0 82 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 7 0 0 57 0 0 0 57 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 75 0 63 7 0 7 25 0 0 7 82 0 0 0 0 % Q
% Arg: 19 0 0 0 0 0 25 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 13 0 0 7 0 0 7 7 0 0 63 32 0 % S
% Thr: 0 0 0 0 0 13 0 75 0 7 7 0 7 7 0 % T
% Val: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _