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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHMP6
All Species:
45.45
Human Site:
Y136
Identified Species:
66.67
UniProt:
Q96FZ7
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96FZ7
NP_078867.2
201
23485
Y136
E
T
Q
E
A
V
E
Y
Q
R
Q
I
D
E
L
Chimpanzee
Pan troglodytes
XP_001152905
208
24321
Y129
E
T
Q
E
A
V
E
Y
Q
R
Q
I
D
E
L
Rhesus Macaque
Macaca mulatta
XP_001110906
257
29807
Y192
E
T
Q
E
A
V
E
Y
Q
R
Q
I
D
E
L
Dog
Lupus familis
XP_850462
476
51202
Y411
E
T
Q
E
A
V
E
Y
Q
R
Q
I
D
E
L
Cat
Felis silvestris
Mouse
Mus musculus
P0C0A3
200
23397
Y136
E
T
Q
E
A
V
E
Y
Q
R
Q
I
D
E
L
Rat
Rattus norvegicus
Q569C1
232
26305
I141
D
I
T
E
Q
Q
D
I
A
Q
E
I
S
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514815
223
25346
Y157
E
T
H
D
A
V
E
Y
Q
R
Q
I
D
E
L
Chicken
Gallus gallus
Q5ZL55
200
23240
Y136
E
T
Q
D
A
V
E
Y
Q
R
Q
I
D
E
I
Frog
Xenopus laevis
Q6GMA4
200
23307
Y136
E
T
Q
E
G
I
E
Y
Q
R
Q
I
D
E
M
Zebra Danio
Brachydanio rerio
Q503V0
206
23961
Y136
E
T
H
D
A
I
E
Y
Q
K
Q
I
D
E
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726213
212
24055
K140
E
T
R
E
G
I
E
K
Q
Q
E
I
D
A
I
Honey Bee
Apis mellifera
XP_394359
209
24436
K137
E
T
R
E
G
I
E
K
Q
K
E
I
D
D
I
Nematode Worm
Caenorhab. elegans
NP_490762
208
24111
Y140
E
T
K
E
A
A
E
Y
Q
E
E
I
S
N
M
Sea Urchin
Strong. purpuratus
XP_782648
206
23787
Y136
D
T
R
E
G
I
E
Y
Q
N
E
I
D
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FY89
216
24591
Y134
D
T
A
E
A
K
A
Y
Q
D
E
L
S
A
I
Baker's Yeast
Sacchar. cerevisiae
Q04272
221
25619
N138
Q
D
Q
I
A
Y
Q
N
E
I
N
E
T
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.8
74.7
37.3
N.A.
92.5
24.5
N.A.
65
81.5
74.1
67.9
N.A.
50.9
46.4
45.1
57.2
Protein Similarity:
100
83.1
76.6
40.1
N.A.
96.5
50.8
N.A.
76.2
92.5
88.5
84.9
N.A.
71.2
72.2
67.7
76.7
P-Site Identity:
100
100
100
100
N.A.
100
20
N.A.
86.6
86.6
80
66.6
N.A.
46.6
46.6
53.3
60
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
93.3
100
93.3
93.3
N.A.
80
86.6
73.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37
29.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.3
53.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
69
7
7
0
7
0
0
0
0
13
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
7
0
19
0
0
7
0
0
7
0
0
75
7
0
% D
% Glu:
75
0
0
75
0
0
82
0
7
7
38
7
0
69
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
25
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
7
0
32
0
7
0
7
0
88
0
0
25
% I
% Lys:
0
0
7
0
0
7
0
13
0
13
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
44
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% M
% Asn:
0
0
0
0
0
0
0
7
0
7
7
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
50
0
7
7
7
0
88
13
57
0
0
0
0
% Q
% Arg:
0
0
19
0
0
0
0
0
0
50
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
7
% S
% Thr:
0
88
7
0
0
0
0
0
0
0
0
0
7
0
0
% T
% Val:
0
0
0
0
0
44
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _