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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHMP6 All Species: 54.55
Human Site: Y69 Identified Species: 80
UniProt: Q96FZ7 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96FZ7 NP_078867.2 201 23485 Y69 L L L K K K R Y Q E Q L L D R
Chimpanzee Pan troglodytes XP_001152905 208 24321 Y62 L L L K K K R Y Q E Q L L D R
Rhesus Macaque Macaca mulatta XP_001110906 257 29807 Y125 L L L K K K R Y Q E Q L L D R
Dog Lupus familis XP_850462 476 51202 Y344 L L L K K K R Y R E Q L L D K
Cat Felis silvestris
Mouse Mus musculus P0C0A3 200 23397 Y69 L L L K K K R Y R E Q L L D R
Rat Rattus norvegicus Q569C1 232 26305 R74 Q A L K R K K R F E K Q L T Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514815 223 25346 Y90 L L L K K M R Y R E Q L L D K
Chicken Gallus gallus Q5ZL55 200 23240 Y69 L L L K K K R Y Q E Q L L D K
Frog Xenopus laevis Q6GMA4 200 23307 Y69 L L L K K K R Y Q E Q L L E K
Zebra Danio Brachydanio rerio Q503V0 206 23961 Y69 L L L K K K R Y Q D Q L L E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_726213 212 24055 Y73 L L L R K K K Y Q E S L L T N
Honey Bee Apis mellifera XP_394359 209 24436 F70 L L L R K K K F Q E Q I L S K
Nematode Worm Caenorhab. elegans NP_490762 208 24111 Y73 L L L K K K R Y Q E K I I D Q
Sea Urchin Strong. purpuratus XP_782648 206 23787 Y69 S L L K K K R Y Q E S L L A K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FY89 216 24591 T67 L A L K K K R T Q E E L L K Q
Baker's Yeast Sacchar. cerevisiae Q04272 221 25619 Y71 F L L K R I H Y Q E H L L Q Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.8 74.7 37.3 N.A. 92.5 24.5 N.A. 65 81.5 74.1 67.9 N.A. 50.9 46.4 45.1 57.2
Protein Similarity: 100 83.1 76.6 40.1 N.A. 96.5 50.8 N.A. 76.2 92.5 88.5 84.9 N.A. 71.2 72.2 67.7 76.7
P-Site Identity: 100 100 100 86.6 N.A. 93.3 33.3 N.A. 80 93.3 86.6 80 N.A. 66.6 60 73.3 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 60 N.A. 93.3 100 100 100 N.A. 80 93.3 100 80
Percent
Protein Identity: N.A. N.A. N.A. 37 29.8 N.A.
Protein Similarity: N.A. N.A. N.A. 58.3 53.8 N.A.
P-Site Identity: N.A. N.A. N.A. 66.6 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 80 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 0 0 0 0 0 0 0 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 7 0 0 0 50 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 94 7 0 0 13 0 % E
% Phe: 7 0 0 0 0 0 0 7 7 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 7 0 0 0 7 0 0 0 0 % H
% Ile: 0 0 0 0 0 7 0 0 0 0 0 13 7 0 0 % I
% Lys: 0 0 0 88 88 88 19 0 0 0 13 0 0 7 44 % K
% Leu: 82 88 100 0 0 0 0 0 0 0 0 82 94 0 0 % L
% Met: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 7 0 0 0 0 0 0 0 75 0 63 7 0 7 25 % Q
% Arg: 0 0 0 13 13 0 75 7 19 0 0 0 0 0 25 % R
% Ser: 7 0 0 0 0 0 0 0 0 0 13 0 0 7 0 % S
% Thr: 0 0 0 0 0 0 0 7 0 0 0 0 0 13 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 82 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _