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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IMP4 All Species: 49.7
Human Site: T89 Identified Species: 84.1
UniProt: Q96G21 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96G21 NP_219484.1 291 33757 T89 D P K V M I T T S R D P S S R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001093227 291 33689 T89 D P K V M I T T S R D P S S R
Dog Lupus familis XP_534545 339 38570 T137 D P K I M I T T S R D P S S R
Cat Felis silvestris
Mouse Mus musculus Q8VHZ7 291 33638 T89 D P K V M I T T S R D P S S R
Rat Rattus norvegicus Q5RJS9 345 39363 T148 S P K I L I T T S D R P H G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521028 287 33234 T85 D P K I M I T T S R D P S S R
Chicken Gallus gallus
Frog Xenopus laevis Q8AVP1 343 40190 T142 T P K I L I T T S D R P R G R
Zebra Danio Brachydanio rerio Q6IQU6 330 38740 T129 N P K V L I T T S D R P R G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKB4 394 45981 F191 E P K V L I T F A D N P V T K
Honey Bee Apis mellifera XP_395323 311 36564 T100 D P K I V I T T S R D P S S R
Nematode Worm Caenorhab. elegans O62518 292 33934 T84 D P K I V I T T S R D P S S R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002297757 293 34097 T89 D P K I L L T T S R D P S A P
Maize Zea mays NP_001136548 293 33879 T89 E P K I L L T T S R N P S A P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53941 290 33464 T92 D P R I I V T T S R D P S T R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.3 81.4 N.A. 97.9 29.8 N.A. 80 N.A. 29.7 29.3 N.A. 26.6 60.1 59.2 N.A.
Protein Similarity: 100 N.A. 99.3 84.3 N.A. 99.3 45.7 N.A. 88.3 N.A. 46.9 46.3 N.A. 44.1 77.8 74.3 N.A.
P-Site Identity: 100 N.A. 100 93.3 N.A. 100 53.3 N.A. 93.3 N.A. 53.3 60 N.A. 40 86.6 86.6 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 66.6 N.A. 100 N.A. 66.6 73.3 N.A. 80 100 100 N.A.
Percent
Protein Identity: 54.2 55.9 N.A. N.A. 51.8 N.A.
Protein Similarity: 72 73 N.A. N.A. 69.4 N.A.
P-Site Identity: 66.6 53.3 N.A. N.A. 66.6 N.A.
P-Site Similarity: 93.3 93.3 N.A. N.A. 100 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 8 0 0 0 0 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 65 0 0 0 0 0 0 0 0 29 65 0 0 0 0 % D
% Glu: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 22 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 65 8 79 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 93 0 0 0 0 0 0 0 0 0 0 0 8 % K
% Leu: 0 0 0 0 43 15 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 36 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % N
% Pro: 0 100 0 0 0 0 0 0 0 0 0 100 0 0 15 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 72 22 0 15 0 79 % R
% Ser: 8 0 0 0 0 0 0 0 93 0 0 0 72 50 0 % S
% Thr: 8 0 0 0 0 0 100 93 0 0 0 0 0 15 0 % T
% Val: 0 0 0 36 15 8 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _