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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IMP4
All Species:
35.15
Human Site:
Y226
Identified Species:
59.49
UniProt:
Q96G21
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96G21
NP_219484.1
291
33757
Y226
T
F
A
N
Q
D
D
Y
I
S
F
R
H
H
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093227
291
33689
Y226
T
F
A
N
Q
D
D
Y
I
S
F
R
H
H
V
Dog
Lupus familis
XP_534545
339
38570
Y274
T
F
A
N
Q
D
D
Y
I
S
F
R
H
H
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHZ7
291
33638
Y226
T
F
A
N
Q
D
D
Y
I
S
F
R
H
H
V
Rat
Rattus norvegicus
Q5RJS9
345
39363
F263
G
H
S
I
G
R
M
F
A
S
L
F
P
H
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521028
287
33234
Y222
T
F
A
N
Q
D
D
Y
I
S
F
R
H
H
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Q8AVP1
343
40190
R279
V
A
T
F
H
N
Q
R
D
Y
I
F
F
R
Y
Zebra Danio
Brachydanio rerio
Q6IQU6
330
38740
R266
V
A
T
F
H
N
Q
R
D
F
I
F
F
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKB4
394
45981
R328
A
V
T
F
H
N
Q
R
D
Y
I
F
F
R
H
Honey Bee
Apis mellifera
XP_395323
311
36564
Y237
T
F
A
N
H
D
D
Y
I
S
F
R
H
H
T
Nematode Worm
Caenorhab. elegans
O62518
292
33934
Y221
T
F
S
N
S
E
D
Y
I
S
F
R
H
H
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002297757
293
34097
Y229
T
F
A
N
Q
S
D
Y
I
S
F
R
H
H
I
Maize
Zea mays
NP_001136548
293
33879
Y229
T
F
A
N
R
D
D
Y
I
S
F
R
H
H
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53941
290
33464
K216
L
F
N
A
G
P
K
K
D
S
E
R
V
I
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.3
81.4
N.A.
97.9
29.8
N.A.
80
N.A.
29.7
29.3
N.A.
26.6
60.1
59.2
N.A.
Protein Similarity:
100
N.A.
99.3
84.3
N.A.
99.3
45.7
N.A.
88.3
N.A.
46.9
46.3
N.A.
44.1
77.8
74.3
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
13.3
N.A.
100
N.A.
0
0
N.A.
0
86.6
80
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
26.6
N.A.
100
N.A.
6.6
6.6
N.A.
6.6
86.6
93.3
N.A.
Percent
Protein Identity:
54.2
55.9
N.A.
N.A.
51.8
N.A.
Protein Similarity:
72
73
N.A.
N.A.
69.4
N.A.
P-Site Identity:
86.6
93.3
N.A.
N.A.
20
N.A.
P-Site Similarity:
93.3
100
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
58
8
0
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
50
65
0
29
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% E
% Phe:
0
72
0
22
0
0
0
8
0
8
65
29
22
0
8
% F
% Gly:
8
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
29
0
0
0
0
0
0
0
65
72
8
% H
% Ile:
0
0
0
8
0
0
0
0
65
0
22
0
0
8
8
% I
% Lys:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
65
0
22
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
43
0
22
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
8
0
22
0
0
0
72
0
22
0
% R
% Ser:
0
0
15
0
8
8
0
0
0
79
0
0
0
0
0
% S
% Thr:
65
0
22
0
0
0
0
0
0
0
0
0
0
0
15
% T
% Val:
15
8
0
0
0
0
0
0
0
0
0
0
8
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
0
15
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _