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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED8
All Species:
36.06
Human Site:
S101
Identified Species:
66.11
UniProt:
Q96G25
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96G25
NP_443109.2
268
29080
S101
E
G
R
V
P
V
F
S
H
E
V
V
P
D
H
Chimpanzee
Pan troglodytes
XP_001173582
268
29088
S101
E
G
R
V
P
V
F
S
H
E
V
V
P
D
H
Rhesus Macaque
Macaca mulatta
XP_001094002
268
28917
S101
E
G
R
V
P
V
F
S
H
E
V
V
P
D
H
Dog
Lupus familis
XP_853421
284
30931
S117
E
G
R
V
P
V
F
S
H
E
V
V
P
D
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7W5
268
29181
S101
E
G
R
V
P
V
F
S
H
E
V
V
P
D
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512637
318
34281
S144
E
G
R
V
P
V
F
S
H
E
V
V
P
D
H
Chicken
Gallus gallus
XP_422404
268
29296
S101
E
G
R
V
P
V
F
S
H
E
V
V
P
D
H
Frog
Xenopus laevis
Q5HZZ6
268
29516
S101
E
G
R
V
P
V
F
S
H
E
V
V
P
D
H
Zebra Danio
Brachydanio rerio
Q6NYT1
267
29384
S102
E
H
R
V
P
V
F
S
H
E
I
V
P
D
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZBT5
252
27930
D87
L
V
S
M
D
R
D
D
T
L
I
N
I
T
E
Honey Bee
Apis mellifera
XP_623274
257
28425
L92
K
D
E
E
L
L
R
L
T
E
G
R
I
P
T
Nematode Worm
Caenorhab. elegans
Q9U1W2
297
33419
N121
Q
G
R
V
M
S
W
N
H
A
L
V
P
E
Y
Sea Urchin
Strong. purpuratus
XP_787301
200
22091
K35
S
D
K
S
P
V
K
K
N
L
I
I
L
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
89.5
89
N.A.
96.6
N.A.
N.A.
76
88.8
77.6
67.9
N.A.
44.7
44.4
21.2
38
Protein Similarity:
100
100
91.7
89.4
N.A.
97.3
N.A.
N.A.
78.9
92.9
86.1
80.2
N.A.
61.5
64.1
41.4
53.7
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
100
86.6
N.A.
0
6.6
40
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
100
93.3
N.A.
13.3
20
80
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
0
0
8
0
8
8
0
0
0
0
0
70
0
% D
% Glu:
70
0
8
8
0
0
0
0
0
77
0
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
70
0
0
0
0
0
0
0
0
% F
% Gly:
0
70
0
0
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
77
0
0
0
0
0
70
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
24
8
16
0
0
% I
% Lys:
8
0
8
0
0
0
8
8
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
8
8
0
8
0
16
8
0
8
0
8
% L
% Met:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
77
0
0
0
0
0
0
0
77
16
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
77
0
0
8
8
0
0
0
0
8
0
0
0
% R
% Ser:
8
0
8
8
0
8
0
70
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
16
0
0
0
0
8
8
% T
% Val:
0
8
0
77
0
77
0
0
0
0
62
77
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _