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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED8
All Species:
37.88
Human Site:
S82
Identified Species:
69.44
UniProt:
Q96G25
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96G25
NP_443109.2
268
29080
S82
V
I
I
P
L
V
L
S
P
D
R
D
E
D
L
Chimpanzee
Pan troglodytes
XP_001173582
268
29088
S82
V
I
I
P
L
V
L
S
P
D
R
D
E
D
L
Rhesus Macaque
Macaca mulatta
XP_001094002
268
28917
S82
V
I
I
P
L
V
L
S
P
D
R
D
E
D
L
Dog
Lupus familis
XP_853421
284
30931
S98
V
I
I
P
L
V
L
S
P
D
R
D
E
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7W5
268
29181
S82
V
I
I
P
L
V
L
S
P
D
R
D
E
D
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512637
318
34281
S125
V
I
I
P
L
V
L
S
P
D
R
D
E
D
L
Chicken
Gallus gallus
XP_422404
268
29296
S82
V
I
I
P
L
V
L
S
P
D
R
D
E
E
I
Frog
Xenopus laevis
Q5HZZ6
268
29516
S82
V
I
I
P
L
L
L
S
P
D
R
D
E
E
I
Zebra Danio
Brachydanio rerio
Q6NYT1
267
29384
S83
V
I
I
P
L
L
L
S
P
D
R
D
E
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZBT5
252
27930
C68
K
I
L
A
K
E
Q
C
P
P
L
R
N
R
T
Honey Bee
Apis mellifera
XP_623274
257
28425
N73
D
K
A
P
N
L
R
N
L
T
V
L
P
L
R
Nematode Worm
Caenorhab. elegans
Q9U1W2
297
33419
Q102
V
L
V
T
Q
R
L
Q
Y
E
P
D
E
T
L
Sea Urchin
Strong. purpuratus
XP_787301
200
22091
S16
L
N
S
F
A
L
L
S
G
Q
I
N
T
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
89.5
89
N.A.
96.6
N.A.
N.A.
76
88.8
77.6
67.9
N.A.
44.7
44.4
21.2
38
Protein Similarity:
100
100
91.7
89.4
N.A.
97.3
N.A.
N.A.
78.9
92.9
86.1
80.2
N.A.
61.5
64.1
41.4
53.7
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
86.6
80
86.6
N.A.
13.3
6.6
33.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
100
100
N.A.
20
20
53.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
70
0
77
0
47
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
8
0
0
77
24
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
77
70
0
0
0
0
0
0
0
8
0
0
0
16
% I
% Lys:
8
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
8
8
0
70
31
85
0
8
0
8
8
0
16
62
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
8
0
0
0
8
8
0
8
% N
% Pro:
0
0
0
77
0
0
0
0
77
8
8
0
8
0
0
% P
% Gln:
0
0
0
0
8
0
8
8
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
8
0
0
0
70
8
0
8
8
% R
% Ser:
0
0
8
0
0
0
0
77
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
0
0
8
0
0
8
8
8
% T
% Val:
77
0
8
0
0
54
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _