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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUS3L
All Species:
48.48
Human Site:
S542
Identified Species:
76.19
UniProt:
Q96G46
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96G46
NP_001155091.1
650
72594
S542
E
Q
R
H
W
D
I
S
S
S
E
R
L
D
I
Chimpanzee
Pan troglodytes
XP_001146456
627
69991
S519
E
Q
R
H
W
D
I
S
S
S
E
R
L
D
I
Rhesus Macaque
Macaca mulatta
XP_001085581
322
35153
R219
K
A
L
Q
Q
Q
L
R
K
R
E
V
R
F
E
Dog
Lupus familis
XP_542144
645
71422
S537
E
Q
R
H
W
D
I
S
S
S
E
R
L
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91XI1
637
71060
S529
E
Q
R
H
W
D
I
S
S
S
E
R
L
D
I
Rat
Rattus norvegicus
Q3KRC5
640
71521
S532
E
Q
R
H
W
D
I
S
S
S
E
R
L
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425899
660
74222
S552
E
Q
R
H
W
D
I
S
S
S
E
R
F
D
I
Frog
Xenopus laevis
Q7ZWS1
640
72538
S532
E
Q
R
H
W
D
I
S
S
T
E
R
F
D
I
Zebra Danio
Brachydanio rerio
NP_956968
660
75360
S552
E
S
R
H
W
D
I
S
S
T
E
R
L
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610000
604
68006
S497
E
K
Q
A
W
S
P
S
S
G
Q
R
Y
E
M
Honey Bee
Apis mellifera
XP_393458
618
71672
S510
E
K
K
L
I
D
I
S
S
T
E
R
F
E
I
Nematode Worm
Caenorhab. elegans
NP_500379
554
62649
R451
W
D
I
S
S
T
E
R
F
D
L
L
K
K
F
Sea Urchin
Strong. purpuratus
XP_793440
655
74135
S520
E
Q
R
H
W
D
I
S
S
S
E
R
F
D
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9T0J6
700
78551
T587
E
Q
R
H
W
D
I
T
S
G
E
R
L
N
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SG01
737
82594
S623
A
G
Q
Y
L
D
K
S
A
T
E
R
L
A
Y
Conservation
Percent
Protein Identity:
100
91.3
42.6
86.3
N.A.
82.3
81.6
N.A.
N.A.
63.1
66.3
63.4
N.A.
45.2
43
45.3
52.5
Protein Similarity:
100
92.6
44.9
91.3
N.A.
87.8
87
N.A.
N.A.
75.7
80.7
76.8
N.A.
59.5
63.2
59.5
66.1
P-Site Identity:
100
100
6.6
93.3
N.A.
100
100
N.A.
N.A.
93.3
86.6
86.6
N.A.
33.3
53.3
0
93.3
P-Site Similarity:
100
100
20
93.3
N.A.
100
100
N.A.
N.A.
93.3
93.3
93.3
N.A.
66.6
80
0
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.4
N.A.
35.1
Protein Similarity:
N.A.
N.A.
N.A.
55
N.A.
50
P-Site Identity:
N.A.
N.A.
N.A.
80
N.A.
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
N.A.
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
7
0
0
0
0
7
0
0
0
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
80
0
0
0
7
0
0
0
54
0
% D
% Glu:
80
0
0
0
0
0
7
0
0
0
87
0
0
14
7
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
0
27
7
7
% F
% Gly:
0
7
0
0
0
0
0
0
0
14
0
0
0
0
0
% G
% His:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
7
0
74
0
0
0
0
0
0
0
74
% I
% Lys:
7
14
7
0
0
0
7
0
7
0
0
0
7
7
0
% K
% Leu:
0
0
7
7
7
0
7
0
0
0
7
7
54
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% P
% Gln:
0
60
14
7
7
7
0
0
0
0
7
0
0
0
0
% Q
% Arg:
0
0
67
0
0
0
0
14
0
7
0
87
7
0
0
% R
% Ser:
0
7
0
7
7
7
0
80
80
47
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
7
0
7
0
27
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% V
% Trp:
7
0
0
0
74
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _