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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DUS3L All Species: 51.21
Human Site: T571 Identified Species: 80.48
UniProt: Q96G46 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96G46 NP_001155091.1 650 72594 T571 D T Q G V E K T R R F L L E W
Chimpanzee Pan troglodytes XP_001146456 627 69991 T548 D T Q G V E K T R R F L L E W
Rhesus Macaque Macaca mulatta XP_001085581 322 35153 A248 P G P T P A A A V P E G T A A
Dog Lupus familis XP_542144 645 71422 T566 D T Q G V E K T R R F L L E W
Cat Felis silvestris
Mouse Mus musculus Q91XI1 637 71060 T558 D T Q G V E R T R R F L L E W
Rat Rattus norvegicus Q3KRC5 640 71521 T561 D T Q G V E R T R R F L L E W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425899 660 74222 T581 D T Q G V E K T R K F L L E W
Frog Xenopus laevis Q7ZWS1 640 72538 T561 D C Q G V E K T R K F M L E W
Zebra Danio Brachydanio rerio NP_956968 660 75360 T581 D T Q G V E K T R N F L L E W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610000 604 68006 T526 D T K G V E T T R R F L L E W
Honey Bee Apis mellifera XP_393458 618 71672 T539 D T R G V E T T R R F M L E W
Nematode Worm Caenorhab. elegans NP_500379 554 62649 L480 V E R T R R F L L E F L S F Q
Sea Urchin Strong. purpuratus XP_793440 655 74135 T549 D S E G V R K T R R F L L E W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9T0J6 700 78551 T616 D T K G V E T T R H F L L E W
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SG01 737 82594 T652 D E L G L N Y T R R F L L E F
Conservation
Percent
Protein Identity: 100 91.3 42.6 86.3 N.A. 82.3 81.6 N.A. N.A. 63.1 66.3 63.4 N.A. 45.2 43 45.3 52.5
Protein Similarity: 100 92.6 44.9 91.3 N.A. 87.8 87 N.A. N.A. 75.7 80.7 76.8 N.A. 59.5 63.2 59.5 66.1
P-Site Identity: 100 100 0 100 N.A. 93.3 93.3 N.A. N.A. 93.3 80 93.3 N.A. 86.6 80 13.3 80
P-Site Similarity: 100 100 0 100 N.A. 100 100 N.A. N.A. 100 93.3 93.3 N.A. 93.3 93.3 20 93.3
Percent
Protein Identity: N.A. N.A. N.A. 38.4 N.A. 35.1
Protein Similarity: N.A. N.A. N.A. 55 N.A. 50
P-Site Identity: N.A. N.A. N.A. 80 N.A. 60
P-Site Similarity: N.A. N.A. N.A. 86.6 N.A. 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 7 7 0 0 0 0 0 7 7 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 87 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 14 7 0 0 74 0 0 0 7 7 0 0 87 0 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 94 0 0 7 7 % F
% Gly: 0 7 0 87 0 0 0 0 0 0 0 7 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 14 0 0 0 47 0 0 14 0 0 0 0 0 % K
% Leu: 0 0 7 0 7 0 0 7 7 0 0 80 87 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 14 0 0 0 % M
% Asn: 0 0 0 0 0 7 0 0 0 7 0 0 0 0 0 % N
% Pro: 7 0 7 0 7 0 0 0 0 7 0 0 0 0 0 % P
% Gln: 0 0 54 0 0 0 0 0 0 0 0 0 0 0 7 % Q
% Arg: 0 0 14 0 7 14 14 0 87 60 0 0 0 0 0 % R
% Ser: 0 7 0 0 0 0 0 0 0 0 0 0 7 0 0 % S
% Thr: 0 67 0 14 0 0 20 87 0 0 0 0 7 0 0 % T
% Val: 7 0 0 0 80 0 0 0 7 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80 % W
% Tyr: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _