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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DUS3L All Species: 50
Human Site: Y605 Identified Species: 78.57
UniProt: Q96G46 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96G46 NP_001155091.1 650 72594 Y605 I N E R P P Y Y L G R D Y L E
Chimpanzee Pan troglodytes XP_001146456 627 69991 Y582 I N E R P P Y Y L G R D Y L E
Rhesus Macaque Macaca mulatta XP_001085581 322 35153 P278 T G L G T S T P P S S P V R T
Dog Lupus familis XP_542144 645 71422 Y600 I N E R P P Y Y L G R D Y L E
Cat Felis silvestris
Mouse Mus musculus Q91XI1 637 71060 Y592 I N E R P P Y Y L G R D Y L E
Rat Rattus norvegicus Q3KRC5 640 71521 Y595 I N E R P P Y Y L G R D Y L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425899 660 74222 Y615 I N E R P P Y Y I G R D Y L E
Frog Xenopus laevis Q7ZWS1 640 72538 Y595 I N E R P P Y Y M G R D Y L E
Zebra Danio Brachydanio rerio NP_956968 660 75360 Y615 I N E R P P F Y M G R D Y L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610000 604 68006 Y560 I N A R P Q K Y R G R D E M E
Honey Bee Apis mellifera XP_393458 618 71672 Y573 I N E R P P F Y K G R D D M E
Nematode Worm Caenorhab. elegans NP_500379 554 62649 F510 I N D R P P R F C G R N E L E
Sea Urchin Strong. purpuratus XP_793440 655 74135 Y583 I N E R P P Y Y V G R D D L E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9T0J6 700 78551 Y650 I N W R P P S Y F G R D D L E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SG01 737 82594 Y686 M N D R P P A Y K G R N E L E
Conservation
Percent
Protein Identity: 100 91.3 42.6 86.3 N.A. 82.3 81.6 N.A. N.A. 63.1 66.3 63.4 N.A. 45.2 43 45.3 52.5
Protein Similarity: 100 92.6 44.9 91.3 N.A. 87.8 87 N.A. N.A. 75.7 80.7 76.8 N.A. 59.5 63.2 59.5 66.1
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. N.A. 93.3 93.3 86.6 N.A. 60 73.3 60 86.6
P-Site Similarity: 100 100 0 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 66.6 86.6 80 93.3
Percent
Protein Identity: N.A. N.A. N.A. 38.4 N.A. 35.1
Protein Similarity: N.A. N.A. N.A. 55 N.A. 50
P-Site Identity: N.A. N.A. N.A. 73.3 N.A. 60
P-Site Similarity: N.A. N.A. N.A. 73.3 N.A. 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 7 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 0 14 0 0 0 0 0 0 0 0 80 20 0 0 % D
% Glu: 0 0 67 0 0 0 0 0 0 0 0 0 20 0 94 % E
% Phe: 0 0 0 0 0 0 14 7 7 0 0 0 0 0 0 % F
% Gly: 0 7 0 7 0 0 0 0 0 94 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 87 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 7 0 14 0 0 0 0 0 0 % K
% Leu: 0 0 7 0 0 0 0 0 34 0 0 0 0 80 0 % L
% Met: 7 0 0 0 0 0 0 0 14 0 0 0 0 14 0 % M
% Asn: 0 94 0 0 0 0 0 0 0 0 0 14 0 0 0 % N
% Pro: 0 0 0 0 94 87 0 7 7 0 0 7 0 0 0 % P
% Gln: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 94 0 0 7 0 7 0 94 0 0 7 0 % R
% Ser: 0 0 0 0 0 7 7 0 0 7 7 0 0 0 0 % S
% Thr: 7 0 0 0 7 0 7 0 0 0 0 0 0 0 7 % T
% Val: 0 0 0 0 0 0 0 0 7 0 0 0 7 0 0 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 54 87 0 0 0 0 54 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _