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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SDSL All Species: 43.33
Human Site: S46 Identified Species: 86.67
UniProt: Q96GA7 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96GA7 NP_612441.1 329 34674 S46 E N V Q P S G S F K I R G I G
Chimpanzee Pan troglodytes XP_001153706 329 34673 S46 E N V Q P S G S F K I R G I G
Rhesus Macaque Macaca mulatta XP_001104628 325 34227 S42 E N V Q P S G S F K I R G I G
Dog Lupus familis XP_543408 329 34358 S46 E N V Q P A G S F K I R G I G
Cat Felis silvestris
Mouse Mus musculus Q8R238 329 34713 S46 E N V Q I A G S F K I R G I G
Rat Rattus norvegicus P09367 363 38414 S39 D S S Q P S G S F K I R G I G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517049 223 23607
Chicken Gallus gallus XP_415319 327 34408 S44 E N V Q P T G S F K I R G V G
Frog Xenopus laevis NP_001091181 328 34826 S39 D N A Q P T G S F K I R G I G
Zebra Danio Brachydanio rerio XP_692090 320 33807 S39 E S S Q P A G S F K I R G I G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798802 321 33814 S40 D N M Q P T A S F K I R G I G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P25379 360 39283 S35 E C L Q P S G S F K S R G I G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 93.9 83.2 N.A. 80.5 55 N.A. 51 63.8 58.6 55 N.A. N.A. N.A. N.A. 54.7
Protein Similarity: 100 99.3 96 88.1 N.A. 88.7 69.1 N.A. 58.3 77.1 73.8 71.1 N.A. N.A. N.A. N.A. 68.6
P-Site Identity: 100 100 100 93.3 N.A. 86.6 80 N.A. 0 86.6 80 80 N.A. N.A. N.A. N.A. 73.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 0 100 93.3 93.3 N.A. N.A. N.A. N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 51.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 80 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 25 9 0 0 0 0 0 0 0 0 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 92 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 84 0 0 0 0 0 92 0 92 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 0 0 0 0 84 0 0 84 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 92 0 0 0 0 0 % K
% Leu: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 67 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 84 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 92 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 92 0 0 0 % R
% Ser: 0 17 17 0 0 42 0 92 0 0 9 0 0 0 0 % S
% Thr: 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 50 0 0 0 0 0 0 0 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _