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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM49 All Species: 34.85
Human Site: S333 Identified Species: 95.83
UniProt: Q96GC9 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96GC9 NP_112200.2 406 46238 S333 A V P G I G P S L Q K P F Q E
Chimpanzee Pan troglodytes XP_001136943 419 47506 S346 A V P G I G P S L Q K P F Q E
Rhesus Macaque Macaca mulatta XP_001109103 406 46196 S333 A V P G I G P S L Q K P F Q E
Dog Lupus familis XP_548240 606 68076 S533 A V P G I G P S L Q K P F Q E
Cat Felis silvestris
Mouse Mus musculus Q99KU0 406 45942 S333 A V P G I G P S L Q K P F Q E
Rat Rattus norvegicus Q91ZQ0 406 45882 S333 A V P G I G P S L Q K P F Q E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415880 406 46341 S333 A I P S I G P S L Q K P F Q E
Frog Xenopus laevis Q6INE8 406 46087 S333 V I P S I G P S L Q K P F Q E
Zebra Danio Brachydanio rerio Q6NYY9 406 45687 S333 V I P G V G A S L Q K P F R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.9 99 64.3 N.A. 94 94.8 N.A. N.A. 85.4 81.5 73.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 96.9 99.2 65.6 N.A. 97.5 97 N.A. N.A. 93.3 89.9 86.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 86.6 80 66.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 86.6 86.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 78 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % F
% Gly: 0 0 0 78 0 100 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 34 0 0 89 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 100 0 0 0 89 0 0 0 0 100 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 100 0 0 0 89 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % R
% Ser: 0 0 0 23 0 0 0 100 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 23 67 0 0 12 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _